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technical note

Single-cell DNA sequencing resolves the genetic complexity underlying CLL progression

Co-occurrence and zygosity of mutations in subclonal populations are frequently missed with bulk sequencing. In high-count monoclonal B-cell lymphocytosis (MBL), these mutations were detectable across all patient samples, on average 41 months prior to chronic lymphocytic leukemia (CLL) progression as a result of single-cell analysis. Learn how the Tapestri Single-cell DNA CLL Panel was used to both gain further insights into patient samples and correlated with a deep targeted sequencing approach.



technical note
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technical note
Single-Cell Measurable Residual Disease (scMRD) Characterization in AML at Unparalleled Resolution
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The State of Cell and Gene Therapy Characterization Survey Report
technical note
scTAM-seq: Leveraging Tapestri for profiling DNA methylation in single-cells
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