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poster
Mission Bio, Inc. South San Francisco, CA, USA

An Automated High-throughput Custom Single-cell Targeted DNA Sequencing Platform to Reveal Rare Clonal Evolution in Cancer and Characterize Mutation Profiles in CRISPR Edited Cells

Many stages of hematopoietic differentiation provide multiple opportunities for
mutations that lead to distinct tumor subtypes. However, standard bulk
population sequencing is hard to identify rare alleles or determine whether
multiple mutations co-occur within the same cell.


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