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Mission Bio, Inc. South San Francisco, CA, USA

High-throughput Single-cell Targeted DNA Sequencing Using an Updated Tapestri TM Platform Reveals Rare Clones and Clonal Evolution for Multiple Blood Cancers

The challenge in precision medicine has been improving the understanding of cancer heterogeneity and clonal evolution, which has major implications in targeted therapy selection and disease monitoring. Single-cell sequencing has the potential to provide unique insights on the cellular and genetic composition, drivers, and signatures of cancer at unparalleled sensitivity.


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Analytical Methods to Identify Tumor Heterogeneity and Rare Subclones in Single-cell DNA Sequencing Data From Targeted Panels
Mission Bio, Inc. South San Francisco, CA, USA
ManiMozhi Manivannan, PhD
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High-throughput Single-cell Targeted DNA Sequencing from Frozen, Fixed and Preserved Solid Tumor Samples Reveals Complex Genomic Variation and Clonal Propagation
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Pedro Mendez, PhD
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Methods to Detect Large Indels and Tandem Duplication in Acute Myeloid Leukemia Using Single-Cell DNA sequencing
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Sombeet Sahu, Ms
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Analytical Methods to Identify Tumor Heterogeneity and Rare Subclones in Single-Cell DNA Sequencing Data from Targeted Panels
Mission Bio, Inc. South San Francisco, CA, USA
Sombeet Sahu, Ms
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