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poster

High-throughput Single-cell Targeted DNA Sequencing from Frozen, Fixed and Preserved Solid Tumor Samples Reveals Complex Genomic Variation and Clonal Propagation


Pedro Mendez

Bulk NGS using archived solid tumor samples is inadequate to fully characterize somatic variation buried in the landscape of cellular populations. Single-cell targeted DNA sequencing provides an essential solution to elucidate and map genomic variation in such materials.


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poster
Single-cell multiomic clonal tracking in myeloma identifies SMM clones that progress to MM and low frequency MM clones with resistance features enabling more precise application of targeted therapies.
Adam Sciambi
poster
High Throughput Single Cell Analysis Workflow for Accurate Measurement of Genotoxicity Arising from Gene Editing Experiments
Saurabh Gulati
poster
Navigating Heterogeneity in Genome Editing Outcomes Using Single-cell Analysis
Brittany Enzmann
poster
Single-Cell Multi-Omic Correlation of Single Nucleotide Variants, Copy Number Variation, and Surface Epitopes for Clonal Profiling of Myeloma
Adam Sciambi; Indira Krishnan; Ben Geller; Daniel Mendoza; Chenchen Yang; Charlie Murphy; Cedric Dos Santos; Vivek S. Chopra; Habib Hamidi; Michael Nixon; Yann Nouet; Todd Druley; Herve Avet-Loiseau
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