Resources | Mission Bio

brochure

Transcriptional Profiling for Safer and Effective Cell and Gene Therapies

FLYER

video

Tracing blood stem cell clones with somatic epimutations

poster

Single-Cell MRD Assessment in AML Reveals Clonal Diversity and Genotype–Phenotype Discordance Missed by Bulk Methods

Adam Sciambi, Daniel Mendoza, Kathryn Thompson, Lan W. Beppu, Benjamin Geller, Indira Krishnan, Lubna Nousheen, Shu Wang, Charlie Murphy, Jerald P. Radich, and Todd E. Druley

brochure

Targeted Single-Cell Gene Expression

FLYER

poster

Comprehensive On-and Off-target Confirmation Using Integrated rhAmpSeq and Targeted DNA Sequencing Single-Cell Technology

Indira Krishnan, Shu Wang, Saurabh Gulati

Scientific Presentation

Interrogating Clonal Evolution in Acute Leukemias through Single-Cell Multi-omic (DNA+Fusion and DNA+Immunophenotype) Analysis

Morgan Drucker, MD

Scientific Presentation

Epitope Editing in Hematopoietic Cells Enables Protection From CD45-directed Immunotherapies For The Treatment Of Blood Cancers And HIV Reservoir Elimination

Dr. Nils Wellhausen

technical note

Assessment of Whole-Genome Copy Number Variation with Tapestri Single-Cell Analysis

poster

Single-cell Multi-omics Analysis Reveals Differential Lineage-specific Vector Copy Number Distribution in CAR-T Cell Products

Yilong Yang; Saurabh Parikh; Khushali Patel; Qawer Ayaz; Lindsey Murphy; Amanda Winters; Terry J. Fry; Mahir Mohiuddin; Hua-Jun He; John Elliott; Benjamin Schroeder; Shu Wang; Chieh-Yuan (Alex) Li

poster

High Throughput Single-cell Assessment of Genome Integrity and Toxicity Events Associated With Edited Cells

Chieh-Yuan (Alex) Li; Saurabh Parikh; Saurabh Gulati; Donjo Ban; Nechama Kalter; Michael Rosenburg; Qawer Ayaz; Joanne Nguyen; Benjamin Miltz; Yang Li1; Madhumita Shrikhande; Edward Szekeres; Ayal Hendel; Benjamin Schroeder; Shu Wang

Scientific Presentation

Leverage Single-cell Multi-parametric Datasets to Advance Heme Oncology Pipelines

Azad Gucwa, PhD

14th World Clinical Biomarkers & Companion Diagnostics Summit (2024)

Scientific Presentation

DKFZ Seminar: Somatic epimutations enable single-cell lineage tracing in native hematopoiesis across the murine and human lifespan

Martina Braun

Scientific Presentation

DKFZ Seminar: Functional phenotyping of genomic variants using multiomic scDNA-scRNA-seq

Dominik Lindenhofer

Scientific Presentation

DKFZ Seminar: Clonal evolution in NPM1c AML

Wout Megchelenbrink

Scientific Presentation

DKFZ Seminar: Leveraging Single-Cell Multiomics for Complex Disease Characterization and Cell Therapy Development

Gema Fuerte

Scientific Presentation

DKFZ Seminar: Subclonal evolution over the course of quadruplet induction in transplant eligible MM patients

Céline Mazzotti

Scientific Presentation

Getting Started with Single-cell DNA Sequencing Series: Assay Development and Transfer

Andrew Reitinger; Holly Tillson, PhD

poster

Single-cell Multiomic Clonal Tracking in Myeloma Identifies SMM Clones that Progress to MM and Low-Frequency MM Clones with Resistance Features Enabling More Precise Application of Targeted Therapies

Adam Sciambi

poster

A novel single-cell measurable residual disease (scMRD) assay for simultaneous DNA mutation and surface immunophenotype profiling

Holly Tillson

Scientific Presentation

Getting Started with Single-cell DNA Sequencing Series: Fundamentals & Wet Lab Needs

Rachel Agoglia, PhD