A major challenge to combating cancer is the tumor’s inherent heterogeneity. Single-cell DNA sequencing allows you to unmask the underlying genetic diversity across cell populations and gain insights into the clonal architecture, mutation co-occurrence, and rare mutations driving tumor progression and therapy resistance.TALK TO A SCIENTIST
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Single-cell DNA sequencing enables you to analyze SNVs, indels, CNVs, and LOH and unambiguously identify variant zygosity, mutational co-occurrence, and rare mutations in thousands of individual cells. With these in-depth insights, solid tumor researchers can elucidate the mechanisms of drug resistance through mutation acquisition, determine how cells transform from benign to malignant states, and reveal the genomic changes enabling cancer cells to metastasize.
It is time to look at the sources of malignancies
Order a predesigned solid tumor panel or customize any panel with your own targets of interest
Select panel content relevant to your specific applications to understand the nature of the disease and potential mechanisms of therapeutic resistance. Mission Bio offers several catalog and virtual panels for solid tumor profiling that are designed based on evidence from public databases and cover some of the most clinically relevant genes.
Jorge Reis-Filho, MD, PhD, Memorial Sloan Kettering Cancer CenterVIEW PUBLICATION
Providing cancer researchers with the only single-cell multi-omics solution that simultaneously detects SNV, CNV, and protein data from the same cell.
Use Tapestri Designer to design a custom panel tailored to your needs.Contact US