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SNV

One Cell. SNVs + Indels.

Because bulk misses the diversity that matters.

The Tapestri Platform is the first and only single-cell DNA sequencing platform to simultaneously detect single nucelotide variants (SNVs) and indels from the same cell. Move beyond the average readout from conventional bulk sequencing, and detect the underlying heterogeneity and rare cell populations in cancer research samples.

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Why Single Cell for SNVs and Indels?

The average readout from conventional bulk sequencing misses the underlying genetic diversity across cell populations. Single-cell DNA sequencing provides the true measure of clonal heterogeneity without inferring or guessing.

Reveal the true clonal architecture in a tumor sample without the assumptions confounded by bulk sequencing.

Identify true mutation co-occurrence in clonal populations
Detect rare subclones down to 0.1% that may be missed by bulk sequencing
Determine the zygosity that matters for your disease research

See how single-cell DNA sequencing reveals clonal evolution in AML patients on gilteritinib.

Cathy Smith, M.D., University of California, San Francisco

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View Panels
Target the diversity that matters with content in a custom panel, or start with one of our pre-designed panels.
Explore Hematology
See how single-cell DNA sequencing transforms the study of hematological malignancies.

The Tapestri Workflow

Plug and play into your existing next-generation sequencing workflow with sample prep and analysis solutions using the Tapestri Platform.

Target Selection
Choose a pre-designed panel or design a
custom panel
SAMPLE
PREP
Simple protocol for cell staining
LIBRARY
PREP
Single workflow
combines dna and protein panels
SEQUENCING
Single sequencing run for snvs, cnvs, and proteins
PIPELINE
Integrated pipeline
for multi-omics analysis
ANALYSIS
powerful analysis and
visualization software

Datasets

Explore the datasets below using single-cell SNV analysis.

NAME
DESCRIPTION
LAST UPDATED

Sample dataset for the Tapestri Single Cell DNA AML panel

10.23.2019

Sample dataset for the Tapestri Single Cell DNA Myeloid panel

10.23.2019

Sample dataset for the Tapestri Single Cell DNA CLL panel

10.23.2019

Sample dataset for a 4-cell line mixed experiment using the Tapestri Single-Cell DNA AML panel

10.23.2019

Featured Resources

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DNA Is Our Foundation

Providing cancer specialists with the only single-cell targeted DNA solution that integrates CNV, SNV, and protein data from the same cell.

Single-cell Genomics (DNA)
SNV + CNV
Characterize genomic heterogeneity using a single, comprehensive platform.
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Single-cell Multi-omics (DNA+)
DNA + RNA
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DNA + Protein
Gain a true multi-omics picture from genotype to phenotype.
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Ready to build a custom panel?

Use Tapestri Designer to design a custom panel tailored to your needs.

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