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Home Resources Posters High-throughput Single-cell Targeted DNA Sequencing from Frozen, Fixed and Preserved…
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High-throughput Single-cell Targeted DNA Sequencing from Frozen, Fixed and Preserved Solid Tumor Samples Reveals Complex Genomic Variation and Clonal Propagation


Pedro Mendez

Bulk NGS using archived solid tumor samples is inadequate to fully characterize somatic variation buried in the landscape of cellular populations. Single-cell targeted DNA sequencing provides an essential solution to elucidate and map genomic variation in such materials.


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Single-cell Multi-omics Analysis Reveals Differential Lineage-specific Vector Copy Number Distribution in CAR-T Cell Products
Yilong Yang; Saurabh Parikh; Khushali Patel; Qawer Ayaz; Lindsey Murphy; Amanda Winters; Terry J. Fry; Mahir Mohiuddin; Hua-Jun He; John Elliott; Benjamin Schroeder; Shu Wang; Chieh-Yuan (Alex) Li
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High Throughput Single-cell Assessment of Genome Integrity and Toxicity Events Associated With Edited Cells
Chieh-Yuan (Alex) Li; Saurabh Parikh; Saurabh Gulati; Donjo Ban; Nechama Kalter; Michael Rosenburg; Qawer Ayaz; Joanne Nguyen; Benjamin Miltz; Yang Li1; Madhumita Shrikhande; Edward Szekeres; Ayal Hendel; Benjamin Schroeder; Shu Wang
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Single-cell Multiomic Clonal Tracking in Myeloma Identifies SMM Clones that Progress to MM and Low-Frequency MM Clones with Resistance Features Enabling More Precise Application of Targeted Therapies
Adam Sciambi
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A novel single-cell measurable residual disease (scMRD) assay for simultaneous DNA mutation and surface immunophenotype profiling
Holly Tillson
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Why Single Cell SNV SNV + CNV DNA + Protein
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