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Publications

FEATURED
PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism
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publication
PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism
Ren, A.A.
Nature
publication
Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia
Wang, F.
Nature Communications
publication
Clonal evolution and heterogeneity in advanced systemic mastocytosis revealed by single-cell DNA sequencing
Lim, K.
Blood Advances
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Joint profiling of DNA and proteins in single cells to dissect genotype-phenotype associations in leukemia
Demaree, B.
Nature Communications
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Single-cell DNA sequencing reveals complex mechanisms of resistance to quizartinib
Peretz, C.A.C
Blood Advances (2021)
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Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome
Alyssa L. Kennedy
Nature Communications (2021)
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Modeling and targeting of erythroleukemia by hematopoietic genome editing
Iacobucci, I.
Blood (2021)
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A JAK2/IDH1-mutant MPN clone unmasked by ivosidenib in an AML patient without antecedent MPN.
Wenbin, X.
Blood Advances (2020)
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Single-cell mutation analysis of clonal evolution in myeloid malignancies.
Miles, L. A.
Nature (2020)
publication
Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia
Wang, F.
BioRxiv (2020)
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Personalized Single-Cell Proteogenomics to Distinguish Acute Myeloid Leukemia from Non-Malignant Clonal Hematopoiesis
Dillon, L.W.
MedRxiv (2020)
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Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics.
Morita, K.
Nature Communications (2020)
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High throughput single-cell detection of multiplex CRISPR-edited gene modifications.
Ten Hacken, E.
Genome Biology (2020)
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Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms.
Taylor, J.
Blood (2020)
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Detectable mutations precede late myeloid neoplasia in aplastic anemia.
Patel, B.A.
Haematologica (2020)
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Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia.
Albertí-Servera, L.
Blood (2021)
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Clonal independence of JAK2 and CALR or MPL mutations in co-mutated myeloproliferative neoplasms demonstrated by single cell DNA sequencing.
Thompson, E.R.
Haematologica (2020)
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Biological and clinical significance of dysplastic hematopoiesis in patients with newly diagnosed multiple myeloma.
Maia, C.
Blood (2020)
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Molecular mechanisms mediating relapse following ivosidenib monotherapy in IDH1-mutant relapsed or refractory AML.
Choe, S.
Blood Advances (2020)
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Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML.
DiNardo, C.D.
Blood (2020)