Publications | Mission Bio

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Impact of Clonal Architecture on Clinical Course and Prognosis in Patients With Myeloproliferative Neoplasms

Luque Paz, Damien

HemaSphere

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Massively parallel base editing to map variant effects in human hematopoiesis

Jorge D. Martin-Rufino

Cell

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Spectrum of clonal hematopoiesis in VEXAS syndrome

Fernanda Gutierrez-Rodrigues

Blood

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Detection and targeting of splicing deregulation in pediatric acute myeloid leukemia stem cells

Inge van der Werf

Cell Reports Medicine

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Base editing screens map mutations affecting interferon-γ signaling in cancer

Matthew A. Coelho

Cancer Cell

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Application of high-throughput single-nucleus DNA sequencing in pancreatic cancer

Haochen Zhang

Nature Communications

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Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia

Donia M. Moujalled

Blood

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Phenotypic signatures of immune selection in HIV-1 reservoir cells

Weiwei Sun

Nature

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Mutated cells mediate distinct inflammatory responses in clonal hematopoiesis

J. Brett Heimlich

BioRxiv

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scTAM-seq enables targeted high-confidence analysis of DNA methylation in single cells

Bianchi A

Genome Biology (2022)

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Hematopoietic differentiation at single-cell resolution in NPM1-mutated AML

Matthieu Duchmann

Blood Cancer Journal

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Single cell genotypic and phenotypic analysis of measurable residual disease in acute myeloid leukemia

Troy T. Robinson

BioRxiv (2022)

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The genomic landscape of pediatric acute lymphoblastic leukemia

Samuel W. Brady

Nature Genetics

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Enhancer deregulation in TET2 Mutant Clonal Hematopoiesis is associated with increased COVID-19 related inflammation severity and mortality

Moritz Binder

BioRxiv

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Single‑cell DNA sequencing reveals order of mutational acquisition in TRAF7/AKT1 and TRAF7/KLF4 mutant meningiomas

Helin Dogan

Acta Neuropathologica

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Detection of early seeding of Richter transformation in chronic lymphocytic leukemia

Ferran Nadeu

Nature Medicine (2022)

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Modeling clonal evolution and oncogenic dependency in vivo in the context of hematopoietic transformation

Bowman RL

BioRxiv (2022)

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Distinct patterns of clonal evolution drive myelodysplastic syndrome progression to secondary acute myeloid leukemia

Guess T

Blood Cancer Discovery (2022)

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High-throughput single-cell sequencing for retroviral reservoir characterization

Droske LE

BioRxiv (2022)

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Monitoring of leukemia clones in B-cell acute lymphoblastic leukemia at diagnosis and during treatment by single-cell DNA amplicon sequencing

Meyers S

HemaSphere (2022)