Publications | Mission Bio

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Phenotypic signatures of immune selection in HIV-1 reservoir cells

Weiwei Sun

Nature

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Mutated cells mediate distinct inflammatory responses in clonal hematopoiesis

J. Brett Heimlich

BioRxiv

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scTAM-seq enables targeted high-confidence analysis of DNA methylation in single cells

Bianchi A

Genome Biology (2022)

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Single cell genotypic and phenotypic analysis of measurable residual disease in acute myeloid leukemia

Troy T. Robinson

BioRxiv (2022)

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The genomic landscape of pediatric acute lymphoblastic leukemia

Samuel W. Brady

Nature Genetics

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Enhancer deregulation in TET2 Mutant Clonal Hematopoiesis is associated with increased COVID-19 related inflammation severity and mortality

Moritz Binder

BioRxiv

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Single‑cell DNA sequencing reveals order of mutational acquisition in TRAF7/AKT1 and TRAF7/KLF4 mutant meningiomas

Helin Dogan

Acta Neuropathologica

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Detection of early seeding of Richter transformation in chronic lymphocytic leukemia

Ferran Nadeu

Nature Medicine (2022)

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Modeling clonal evolution and oncogenic dependency in vivo in the context of hematopoietic transformation

Bowman RL

BioRxiv (2022)

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Distinct patterns of clonal evolution drive myelodysplastic syndrome progression to secondary acute myeloid leukemia

Guess T

Blood Cancer Discovery (2022)

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High-throughput single-cell sequencing for retroviral reservoir characterization

Droske LE

BioRxiv (2022)

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Monitoring of leukemia clones in B-cell acute lymphoblastic leukemia at diagnosis and during treatment by single-cell DNA amplicon sequencing

Meyers S

HemaSphere (2022)

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Single-cell analysis reveals selection of TP53-mutated clones after MDM2 inhibition

Maslah N

Blood Advances (2022)

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Application of high-throughput, high-depth, targeted single-nucleus DNA sequencing in pancreatic cancer

Zhang H

BioRxiv (2022)

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Developmental venous anomalies are a genetic primer for cerebral cavernous malformations

Snellings D.A.

Nature (2022)

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Clonal hematopoiesis, myeloid disorders and BAX-mutated myelopoiesis in patients receiving venetoclax for CLL

Blombery P

Blood (2022)

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Single cell proteogenomic sequencing identifies a relapse-fated AML subclone carrying FLT3-ITD with CN-LOH at chr13q

TaeHyung Kim

British Society for Hematology

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Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

Zhang Q

Nature (2022)

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Reconstructing mutational lineages in breast cancer by multi-patient-targeted single cell DNA sequencing

Leighton J

BioRxiv (2022)

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Mechanisms of resistance to noncovalent Bruton’s tyrosine kinase inhibitors

Wang E

New England Journal of Medicine (2022)