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Publications

FEATURED
Application of high-throughput, high-depth, targeted single-nucleus DNA sequencing in pancreatic cancer
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publication
Distinct patterns of clonal evolution drive myelodysplastic syndrome progression to secondary acute myeloid leukemia
Guess T
Blood Cancer Discovery (2022)
publication
High-throughput single-cell sequencing for retroviral reservoir characterization
Droske LE
BioRxiv (2022)
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scTAM-seq enables targeted high-confidence analysis of DNA methylation in single cells
Bianchi A
BioRxiv (2022)
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Monitoring of leukemia clones in B-cell acute lymphoblastic leukemia at diagnosis and during treatment by single-cell DNA amplicon sequencing
Meyers S
HemaSphere (2022)
publication
Single-cell analysis reveals selection of TP53-mutated clones after MDM2 inhibition
Maslah N
Blood Advances (2022)
publication
Application of high-throughput, high-depth, targeted single-nucleus DNA sequencing in pancreatic cancer
Zhang H
BioRxiv (2022)
publication
Developmental venous anomalies are a genetic primer for cerebral cavernous malformations
Snellings D.A.
Nature (2022)
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Clonal hematopoiesis, myeloid disorders and BAX-mutated myelopoiesis in patients receiving venetoclax for CLL
Blombery P
Blood (2022)
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Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia
Zhang Q
Nature (2022)
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Reconstructing mutational lineages in breast cancer by multi-patient-targeted single cell DNA sequencing
Leighton J
BioRxiv (2022)
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Mechanisms of resistance to noncovalent Bruton’s tyrosine kinase inhibitors
Wang E
New England Journal of Medicine (2022)
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Molecular characterization of acquired resistance to KRAS G12C inhibition in gastrointestinal cancers
Misale S
Research Square (2022)
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Preneoplastic somatic mutations including MYD88L265P in lymphoplasmacytic lymphoma
Rodriguez S
Science Advances (2022)
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Single-cell sequencing demonstrates complex resistance landscape in CLL and MCL treated with BTK and BCL2 inhibitors
Thompson ER
Blood Advances (2021)
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Gain-of-function mutations in RPA1 cause a syndrome with short telomeres and somatic genetic rescue
Sharma R
Blood (2021)
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Diverse alterations associated with resistance to KRAS(G12C) inhibition
Zhao Y
Nature (2021)
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Clinical evolution, genetic landscape and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes
Sahoo S.S.
Nature Medicine (2021)
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Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma
Marin-Bejar, O.
Cancer Cell (2021)
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Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias
Thijssen, R.
Blood (2021)
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Personalized single-cell proteogenomics to distinguish acute myeloid leukemia from nonmalignant clonal hematopoiesis
Dillon, L.W.
Blood Cancer Discovery (2021)
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