Publications Archive | Mission Bio

publication

Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia.

Albertí-Servera, L.

Blood (2020)

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Clonal independence of JAK2 and CALR or MPL mutations in co-mutated myeloproliferative neoplasms demonstrated by single cell DNA sequencing.

Thompson, E.R.

Haematologica (2020)

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Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms.

Taylor, J.

Blood (2020)

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Biological and clinical significance of dysplastic hematopoiesis in patients with newly diagnosed multiple myeloma.

Maia, C.

Blood (2020)

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Distinct genetic pathways define pre-leukemic and compensatory clonal hematopoiesis in Shwachman-Diamond syndrome

Kennedy, A. L.

BioRxiv (2020)

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Molecular mechanisms mediating relapse following ivosidenib monotherapy in IDH1-mutant relapsed or refractory AML.

Choe, S.

Blood Advances (2020)

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Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML.

DiNardo, C.D.

Blood (2020)

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Single-cell mutational profiling enhances the clinical evaluation of AML MRD.

Ediriwickrema, A.

Blood Advances (2020)

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Joint profiling of proteins and DNA in single cells reveals extensive proteogenomic decoupling in leukemia

Demaree, B.

BioRxiv (2020)

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Single cell mutational profiling delineates clonal trajectories in myeloid malignancies

Miles, L. A.

BioRxiv (2020)

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Clonal Evolution of Acute Myeloid Leukemia Revealed by High-Throughput Single-Cell Genomics

Morita, K.

BioRxiv (2020)

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V211D Mutation in MEK1 Causes Resistance to MEK Inhibitors in Colon Cancer.

Gao, Y.

Cancer Discovery (2019)

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Polyclonal Heterogeneity: The New Norm for Secondary Clinical Resistance to Targeted Monotherapy in Relapsed Leukemia?

Wei, A.H.

Cancer Discovery (2019)

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Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia.

McMahon, C.M.

Cancer Discovery (2019)

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Clonal Evolution and Changes in Two AML Patients Detected with A Novel Single-Cell DNA Sequencing Platform.

Xu, L.

Scientific Reports (2019)

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High-throughput single-cell DNA sequencing of acute myeloid leukemia tumors with droplet microfluidics.

Pellegrino, M.

Genome Research (2018)

publication

Lgr6 is a stem cell marker in mouse skin squamous cell carcinoma.

Huang, P.Y.

Nature Genetics (2017)

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RNA-Seq following PCR-based sorting reveals rare cell transcriptional signatures.

Pellegrino, M.

BMC Genomics (2016)

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Microfluidic droplet enrichment for targeted sequencing.

Eastburn, D.J.

Nucleic Acids Research (2015)

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Identification and genetic analysis of cancer cells with PCR-activated cell sorting.

Eastburn, D.J.

Nucleic Acids Research (2014)