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Publications

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Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma

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Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma

Marin-Bejar, O.

Cancer Cell (2021)

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

Personalized single-cell proteogenomics to distinguish acute myeloid leukemia from nonmalignant clonal hematopoiesis

Blood Cancer Discovery (2021)

PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism

Leukemia stemness and co-occurring mutations drive resistance to IDH inhibitors in acute myeloid leukemia

Nature Communications (2021)

Clonal evolution and heterogeneity in advanced systemic mastocytosis revealed by single-cell DNA sequencing

Blood Advances (2021)

Joint profiling of DNA and proteins in single cells to dissect genotype-phenotype associations in leukemia

Nature Communications (2021)

Single-cell DNA sequencing reveals complex mechanisms of resistance to quizartinib

Blood Advances (2021)

Distinct genetic pathways define pre-malignant versus compensatory clonal hematopoiesis in Shwachman-Diamond syndrome

Alyssa L. Kennedy

Nature Communications (2021)

Modeling and targeting of erythroleukemia by hematopoietic genome editing

A JAK2/IDH1-mutant MPN clone unmasked by ivosidenib in an AML patient without antecedent MPN.

Blood Advances (2020)

Single-cell mutation analysis of clonal evolution in myeloid malignancies.

Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics.

Nature Communications (2020)

High throughput single-cell detection of multiplex CRISPR-edited gene modifications.

Genome Biology (2020)

Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms.

Detectable mutations precede late myeloid neoplasia in aplastic anemia.

Haematologica (2020)

Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia.

Albertí-Servera, L.

Clonal independence of JAK2 and CALR or MPL mutations in co-mutated myeloproliferative neoplasms demonstrated by single cell DNA sequencing.

Haematologica (2020)

Biological and clinical significance of dysplastic hematopoiesis in patients with newly diagnosed multiple myeloma.

Molecular mechanisms mediating relapse following ivosidenib monotherapy in IDH1-mutant relapsed or refractory AML.

Blood Advances (2020)