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technical note

In-depth quantification of cell and gene therapy DNA integrations enabled with single-cell sequencing

The Tapestri Platform provides an unprecedented level of quantification of DNA integrations in significantly less time compared to other techniques such as qPCR and does so at single cell resolution. These characteristics allow for the rapid optimization of transduction protocols or homology directed repair (HDR) protocols during therapy development and streamlined testing and release of transduced or integrated cells during manufacturing of therapeutic products.


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technical note
BGI Sequencing Platforms Produce High-Quality Performance Metrics from Tapestri Single-cell Experiments
technical note
Single-cell DNA Analysis of a Novel Acute Erythroid Leukemia (AEL) CRISPR Induced Mouse Model
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Deep understanding of cell and gene therapy genome editing protocols enabled with single-cell sequencing
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Single-cell analysis of mouse organoid models for preclinical oncology research