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technical note

In-depth quantification of cell and gene therapy DNA integrations enabled with single-cell sequencing

The Tapestri Platform provides an unprecedented level of quantification of DNA integrations in significantly less time compared to other techniques such as qPCR and does so at single cell resolution. These characteristics allow for the rapid optimization of transduction protocols or homology directed repair (HDR) protocols during therapy development and streamlined testing and release of transduced or integrated cells during manufacturing of therapeutic products.


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technical note
Deep understanding of cell and gene therapy genome editing protocols enabled with single-cell sequencing
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Model organisms and patient-derived xenografts for preclinical oncology research
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Correlations between genomic variants and protein expression in AML patient samples
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AML subpopulations defined by SNV, CNV, and protein expression
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