Solid tumors often show multiple levels of heterogeneity. This heterogeneity can contribute to molecular lesions play a role in driving cancer evolution and treatment response. With single-cell DNA sequencing, you can discern each patient’s response profile to better study therapy response, resistance, and relapse.
TALK TO A SCIENTISTMetastatic cancer in solid tumors leads to the clonal evolution of mutations at different sites in the body. Understanding the phylogeny of mutations at different cancer sites reveals how the metastases developed and is easily reconstructed with single-cell DNA-seq. Zygosity and co-occurrence of the mutations within the clones are revealed. In addition, along with SNVs and indels, CNVs, LOH, and protein expression give a detailed picture of the nature of each individual cancer cell.
It is time to look at the sources of maligancies
Order a predesigned solid tumor panel or customize any panel with your own targets
Select panel content relevant to your specific sequencing applications to understand the nature of the disease and potential mechanisms of therapeutic resistance. We offer several catalog targeted panels for solid tumor profiling based on public databases and actionable clinical targets.
Jorge Reis-Filho, M.D., Ph.D, Memorial Sloan Kettering Cancer Center
VIEW PUBLICATIONProviding cancer researchers with the only single-cell multi-omics solution that simultaneously detects SNV, CNV, and protein data from the same cell.
Use Tapestri Designer to design a custom panel tailored to your needs.
Contact US
