On The Drop

Recently published in the New England Journal of Medicine, researchers from Stanford University found that comprehensive genetic characterization of T-cell lymphomas after CAR T-cell therapy remains essential for understanding the risk of potential tumors with this therapy. Our own Dr. Todd Druley sat down with two of the publication's authors, Dr. Ash Alizadeh and Dr. Mark Hamilton, to discuss their findings.

In this roundtable, hear from Hervé Avet-Loiseau, MD, PhD, Head of the Laboratory for Genomics in Myeloma, University Cancer Center of Toulouse, Felipe Prósper, MD, PhD, Co-Director of Hematology and Cell Therapy, Clínica Universidad de Navarra, and Cedric Dos Santos, PhD, Director AML/MDS/MM, Translational Medicine, Genentech, as they discuss real-world studies enabling clonal surveillance for precision therapy insights and measurable residual disease surveillance, bridging research and drug development to explore the clinical impact and future horizons of single-cell analysis in AML and MM diagnostics & therapies.

In this episode, we sit down with Senior Director of Clinical Applications, Aaron Llanso. Aaron discusses his untraditional career path, his personal experience with cancer, and how truly impactful the Tapestri scMRD Assay for AML can be for a patient's journey.

In our latest installment in our Hills and Valleys of Precision Medicine series, Ania Wronski, PhD, chats with our Director of Product Development Nicole Ovadia, PhD, about our Tapestri Single-cell Multi-omics MRD (scMRD) Assay for AML.

In this episode, we sit down with Mission Bio's Chief Medical Officer, Dr. Todd Druley. Todd discusses his background in pediatric oncology and molecular genetics, why he decided to join Mission Bio, and how we're tackling some of the biggest challenges in precision medicine.

In this episode, we sit down with Mission Bio’s CEO, Yan Zhang, to discuss her first nine months at the helm of Mission Bio. Yan chats with about her background in the life sciences, her decision to join Mission Bio, and the challenges she has faced on her journey to becoming a CEO.

In this Researcher Spotlight, we chat with Sushree Sahoo from the St. Jude Children’s Research Hospital in Memphis, Tennessee. Sushree specializes in translational, molecular genetics, and is passionate about uncovering the underlying mechanisms of diseases like cancer. We discuss somatic genetic rescue in her paper, “Clinical evolution, genetic landscape, and trajectories of clonal hematopoiesis in SAMD9/SAMD9L syndromes”

This week, we’re excited to explore the origins of Women of Mission Bio Group (WOMO) and are delighted to speak with one of it’s founders Samantha Mason, Mission Bio’s Director of Software Products. Samantha founded WOMO as a safe space for women, by women, to come together from across the organization where they can openly discuss topics pertaining to women, network, and providing leadership guidance during times of adversity.

In this Researcher Spotlight, we speak with Linde Miles from the Memorial Sloan Kettering Cancer Center, New York. Linde has participated in the largest study ever to investigate the genetic roots of Leukemia at the single-cell level. Last October, she co-authored a paper in Nature titled "Single-cell mutation analysis of clonal evolution in myeloid malignancies".

In this Researcher Spotlight, we speak with Doug Marchuk and Daniel Snellings from the Duke University School of Medicine. Doug and Daniel’s work centers on the genetics that underlies cardiovascular diseases. They recently published a paper in Nature entitled, PIK3CA and CCM Mutations Fuel Cavernomas Through a Cancer-Like Mechanism.

Last month, Mission Bio launched it’s PAD (Pharma Assay Development) solutions. In this weeks episode, Harsha Kavuri tackles some of the exciting benefits and capabilities PAD may be used in bringing effective therapies to cancer patients.

In this Researcher Spotlight, we speak with Dr. Ross Levine from Memorial Sloan Kettering. Dr. Levine aims to better understand the genetic basis of myeloid malignancies and discusses his journey in hematological oncology and how using single-cell analysis has furthered advancements in his research.

In this Researcher Spotlight, we chat with Ilaria Iacobucci, PhD from the St. Jude Children’s Research Hospital about pairing single-cell analysis with CRISPR, women in science, and pandemic woes.