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poster

High-throughput Single-cell Targeted DNA Sequencing from Frozen, Fixed and Preserved Solid Tumor Samples Reveals Complex Genomic Variation and Clonal Propagation


Pedro Mendez
AACR (2019)

Bulk NGS using archived solid tumor samples is inadequate to fully characterize somatic variation buried in the landscape of cellular populations. Single-cell targeted DNA sequencing provides an essential solution to elucidate and map genomic variation in such materials.


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poster
Amplicon design algorithm for single cell targeted DNA sequencing using machine learning
Shu Wang
AACR (2020)
poster
Improvements in variant calling sensitivity and specificity in single-cell DNA sequencing using deep learning
Manimozhi Manivannan
AACR (2020)
poster
Powerful insights with single-cell multi-omics: Co-detecting both genotype and phenotype from the same cell
James Flynn, PhD
AGBT (2020)
poster
Subclonal identification of driver mutations and copy number variations from single-cell DNA sequencing of tumors
James Flynn, PhD
ABRF (2020)
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