poster

Method to analyze mutational and phenotypic profiles from single cell for clonal evolution

Saurabh Parikh

This poster demonstrates the capability of the Tapestri Platform multi-omics workflow (which analyzes the DNA and protein information from the same cells) to discriminate cell populations. Using a two-donor PBMC mixture as a model system, we show how processing on Tapestri identifies two clones using the genetic variants and multiple cell types including T-cells, B-cells, monocytes, and NK-cells using phenotypic expression. Moreover, Tapestri identified the proportion of each cell type belonging to each of the two donors.

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poster

Single-cell Multiomic Clonal Tracking in Myeloma Identifies SMM Clones that Progress to MM and Low-Frequency MM Clones with Resistance Features Enabling More Precise Application of Targeted Therapies

Adam Sciambi

poster

A novel single-cell measurable residual disease (scMRD) assay for simultaneous DNA mutation and surface immunophenotype profiling

Holly Tillson

poster

Single-cell multiomic clonal tracking in myeloma identifies SMM clones that progress to MM and low frequency MM clones with resistance features enabling more precise application of targeted therapies.

Adam Sciambi

poster

High Throughput Single Cell Analysis Workflow for Accurate Measurement of Genotoxicity Arising from Gene Editing Experiments

Saurabh Gulati

Method to analyze mutational and phenotypic profiles from single cell for clonal evolution

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