Tapestri Single-cell DNA Acute Lymphoblastic Leukemia (ALL) Published Panel was designed by the Jan Cools Lab at the Center for Cancer Biology, Vlaams Instituut voor Biotechnologie (VIB). The ALL Published Panel is featured in a study published in Blood, “Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia.” Researchers assessed ALL variant hotspots across 305 genomic regions by analyzing 108,188 cells in 25 samples from 8 T-ALL patients.
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Advance your understanding of the genetic heterogeneity underpinning acute lymphoblastic leukemia (ALL) by targeting 112 genes with 305 amplicons for single-cell sequencing. The ALL Published Panel is designed to target the most commonly mutated hotspots in ALL, as defined by COSMIC and PeCan databases.
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Use Tapestri Designer to add or remove content from existing catalog panels and make this panel your own with content that is relevant to your research. Or start from scratch and upload your human (hg19) or mouse (mm10) targets using gene names, genomic coordinates, or SNV IDs. Target anywhere in the whole human or mouse genome and advance your research with targeted single-cell DNA sequencing.
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