Targeted Single-Cell Gene Expression

Single-cell targeted genotype & gene expression— all in one assay

The success of introducing a new therapy to the market hinges on a multifaceted approach that integrates biomarker selection, mechanistic disease understanding, and proactive resistance management. Mechanisms of action and resistance—such as clonal evolution, activation of alternative signaling pathways, or epigenetic reprogramming—often emerge during treatment but are difficult to predict. Traditional research methods rely on bulk transcriptomics, proteomics, or genomic sequencing— each providing a partial, averaged-out view. Leveraging Mission Bio’s new Pharma Assay Development (PAD) services to analyze targeted genotype & gene expression in a single assay, drug developers can gain the confidence to move their oncology pipeline forward.