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Hematology Panels

Because single-cell insights are critical to determining the source of resistance, response, and relapse

The complexity of cancer is vast, and it is critical to measure the network of biological interactions accurately and minimize inferences. With Mission Bio’s hematology panels, you can simultaneously analyze DNA mutations and protein expression, to discover clonal networks otherwise obfuscated by bulk methods done in parallel. By connecting genotype to phenotype at the single-cell level, you can gain comprehensive insights into disease progression, development of resistance, and minimal residual disease (MRD).


NEW: Check out the latest Tapestri Platform updates.


Why Single Cell for Hematologic Malignancy Applications?

For hematologic malignancies, simultaneous DNA and protein analysis from the same cell can resolve the zygosity of mutations, determine if mutations co-occur or are mutually exclusive, and correlate that to immunophenotypes. With these insights, phylogenetic trees can be reconstructed to determine the order of acquisition of these mutations. Fish plots show how clonal architecture changes throughout the course of treatment. And monitoring during remission poses great promise for sensitive MRD detection.

It is time to get a holistic view of cancer

Track clonal evolution and reconstruct phylogenetic trees click to zoom
Track clonal evolution and reconstruct phylogenetic trees
Clonal evolution of acute myeloid leukemia revealed by high-throughput single-cell genomics

Dr. Koichi Takahashi, MD Anderson Cancer Center
Reveal therapy resistance mechanisms through course of treatment click to zoom
Reveal therapy resistance mechanisms through course of treatment
Clonal selection with Ras pathway activation mediates secondary clinical resistance to selective FLT3 inhibition in AML

Dr. Cathy Smith, Dr. Alexander Perl, UCSF, UPenn
Monitor disease during remission to track MRD click to zoom
Monitor disease during remission to track MRD
Single-cell mutational profiling enhances the clinical evaluation of AML MRD

Dr. Ravi Majeti, Stanford

Hematology Panels

Order predesigned hematology panels or customize any panel with your own targets

Select panel content relevant to your specific sequencing applications to understand the nature of the disease and potential mechanisms of therapeutic resistance. We offer several catalog targeted panels based on public databases and actionable clinical targets.

Available DNA Hematology Panels
Tapestri Single-cell DNA Catalog Panels
Predesigned and ready-to-ship hematology panels covering the most commonly implicated genes in hematologic malignancies. Wet lab-tested to assure performance.
Acute Myeloid Leukemia
Chronic Lymphocytic Leukemia
NEW: Tapestri Single-cell DNA Published Panels
Predesigned and ready-to-ship hematology panels designed by leading researchers of hematologic malignancies. Featured in peer-reviewed publications from leading research institutes.
Acute Lymphoblastic Leukemia (Cools, VIB)
Chronic Lymphocytic Leukemia (Abdel-Wahab, MSKCC)
Myeloid (Takahashi, MDACC)
Myeloid Clonal Evolution (Levine, MSKCC)
Myeloproliferative Neoplasms (Blombery, Peter Mac)
Tapestri Single-cell DNA Virtual Design Panels
Predesigned and build-to-order panels for additional indications in hematologic malignancies.
Acute Lymphoblastic Leukemia
Chronic Myeloid Leukemia
Classic Hodgkin’s Lymphoma
Diffuse Large B-Cell Lymphoma
Follicular Lymphoma
Mantle Cell Lymphoma
Multiple Myeloma
Myelodysplastic Syndromes
Myeloproliferative Neoplasms
T-Cell Lymphoma
Tapestri Single-cell DNA Custom Panels
Fully customizable hematology panels for maximum flexibility. Easily order a custom panel using Tapestri Designer.
Learn More
Available Protein Hematology Panels
Concurrently measure proteins by ordering the ready-to-ship TotalSeq™-D Heme Oncology Cocktail or by configuring your own antibody cocktail from a growing catalog of pre-optimized antibody oligonucleotide conjugates.
TotalSeq™-D Heme Oncology Cocktail from BioLegend
TotalSeq™-D Catalog Antibodies from BioLegend

Hear from a hematological pathologist on how single-cell multi-omics can transform cell therapies for leukemias.

Katherine D. Cummins, MD, FRACP, FRCPA, University of Pennsylvania


DNA Is Our Foundation

Providing cancer researchers with the only single-cell multi-omics solution that simultaneously detects SNV, CNV, and protein data from the same cell.

DNA helix icon
Single-cell Genomics (DNA)
Detect rare clonal populations and identify co-occurrence and zygosity.
Characterize genomic heterogeneity using a single comprehensive platform.
Single cell icon
Single-cell Multi-omics (DNA+)
DNA + Protein
Gain a true multi-omics picture from genotype to phenotype.
Solid Tumors
Profiling enables high resolution of the genomic diversity in a variety of tumor types.
Genome Editing
Precision tools provide quality control, ensuring the appropriate edits are incorporated.

Featured Resources


Ready to learn more?

Use Tapestri Designer to design a custom panel tailored to your needs.

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