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Announcing new Tapestri Platform updates including lowered input threshold and expanded heme-onc menu. Learn More
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Untangle the Complexity of Cancer.

Determine the sources of resistance, response, and relapse

Tapestri single-cell DNA panels and protein panels are highly sensitive and customizable panels that enable true multi-omics analysis on the Tapestri Platform. Whether identifying co-mutation patterns and zygosity in subclones, or cellular identities and subtle cell states, Tapestri single-cell DNA panels and protein panels can be applied across a wide range of discovery and translational research applications.

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Tapestri Single-cell DNA and Protein Panels

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The only comprehensive single-cell DNA platform
Identify SNVs, indels, CNVs, LOH, and translocations from the DNA of thousands of individual cells
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The only single-cell DNA and protein platform
Incorporate protein panels and a simple cell-staining protocol to profile genotype and phenotype simultaneously in single cells
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Flexibility across analytes and applications
Focus on your regions of interest with targeted content that allows flexibility in experimental design and budget

Choose the Panel Type that Fits your Needs

Tapestri Single-cell DNA panels are available in a ready-to-ship or built-to-order format. Select from Tapestri Single-cell DNA Catalog Panels predesigned and wet lab-tested to get your lab up and running with minimal time and effort. With the new Tapestri Single-cell DNA Published Panels, researchers of hematologic malignancies can now easily start with single-cell DNA panels designed by leading researchers and verified for performance through a peer-review publication. If you require more flexibility, consider the predesigned but customizable Tapestri Single-cell DNA Virtual Design Panels. For maximum versatility, create a Tapestri Single-cell DNA Custom Panel for human, mouse, or any other reference genome of your choice.

Oligo-conjugated antibodies from BioLegend can be integrated into your Tapestri experiments to enable concurrent measurement of proteins, uncovering both genotypes and phenotypes from the same cell, across thousands of cells.

Hematologic Malignancies

Clonal evolution is foundational to disease progression in hematologic malignancies which can impact therapy response, resistance, relapse and residual disease. Tapestri single-cell hematology panels provide insight into disease drivers and mutation patterns missed during bulk sequencing. By interrogating clonal architecture, rare subclones associated with remission and therapeutic resistance can be identified.

Available DNA Panels
Ready-to-Ship
Tapestri Single-cell DNA Catalog Panels
Predesigned and ready-to-ship panels covering the most commonly implicated genes in hematologic malignancies. Wet lab-tested to assure performance.
Acute Myeloid Leukemia
Chronic Lymphocytic Leukemia
Myeloid
NEW: Tapestri Single-cell DNA Published Panels
Predesigned and ready-to-ship panels designed by leading researchers of hematologic malignancies. Featured in peer-reviewed publications from leading research institutes.
Acute Lymphoblastic Leukemia (Jan Cools, VIB)
Myeloid Clonal Evolution (Ross Levine, MSKCC)
Myeloproliferative Neoplasms (Piers Blombery, Peter Mac)
Build-to-Order
Tapestri Single-cell DNA Virtual Design Panels
Predesigned and build-to-order panels for additional indications in hematologic malignancies.
Acute Lymphoblastic Leukemia
Chronic Myeloid Leukemia
Classic Hodgkin’s Lymphoma
Diffuse Large B-Cell Lymphoma
Follicular Lymphoma
Mantle Cell Lymphoma
Multiple Myeloma
Myelodysplastic Syndromes
Myeloproliferative Neoplasms
T-Cell Lymphoma
Tapestri Single-cell DNA Custom Panels
Fully customizable panels for maximum flexibility. Easily order a custom panel using Tapestri Designer.
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Available Protein Panels
Concurrently measure proteins by ordering the ready-to-ship TotalSeq™-D Heme Oncology Cocktail or by configuring your own antibody cocktail from a growing catalog of pre-optimized antibody oligonucleotide conjugates.
TotalSeq™-D Heme Oncology Cocktail from BioLegend
TotalSeq™-D Catalog Antibodies from BioLegend

Solid Tumors

Cellular heterogeneity in solid tumor cancers impacts clonal evolution and patient outcomes. Single-cell DNA solid tumor profiling enables high resolution of the genomic diversity in a variety of tumor types by interrogating specific regions in oncogenes and tumor suppressors.

Available DNA Panels
Ready-to-Ship
Tapestri Single-cell DNA Catalog Panel
Predesigned and ready-to-ship panels covering the most commonly implicated genes in solid tumor cancer and wet lab-tested to assure performance.
Tumor Hotspot
Build-to-Order
Tapestri Single-cell DNA Custom Panels
Fully customizable panels for maximum flexibility. Easily order a custom panel using Tapestri Designer.
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Custom Panels with Tapestri Designer

With the intuitive Tapestri Designer software, your custom design can be completed within minutes. Primer design algorithms and multiplex PCR biochemistry have been optimized for the Tapestri Platform so that you can be confident of high design coverage and high panel uniformity. Design a DNA panel against human, mouse or any other custom reference genomes of your choice. Custom DNA panels can be paired with oligo-conjugated antibodies to enable simultaneous detection of genotype and phenotype from the same cell for true single-cell multi-omics insights.

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Hear how the order of mutatation acquisition was unambiguously resolved with single-cell sequencing.

Linde Miles, Ph.D, Memorial Sloan Kettering Cancer Center

WATCH VIDEO Learn more about Myeloid Clonal Evolution Published Panel
CAPABILITIES

DNA Is Our Foundation

Providing cancer researchers with the only single-cell multi-omics solution that simultaneously detects SNV, CNV, and protein data from the same cell.

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Single-cell Genomics (DNA)
SNV
Detect rare clonal populations and identify co-occurrence and zygosity.
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SNV + CNV
Characterize genomic heterogeneity using a single, comprehensive platform.
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Single-cell Multi-omics (DNA+)
DNA + Protein
Gain a true multi-omics picture from genotype to phenotype.
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