Resources | Mission Bio

publication

Distinct patterns of clonal evolution drive myelodysplastic syndrome progression to secondary acute myeloid leukemia

Guess T et al.

Blood Cancer Discovery (2022)

publication

High-throughput single-cell sequencing for retroviral reservoir characterization

Droske LE et al.

BioRxiv (2022)

Scientific Presentation

CHIP’ing away at somatic mosaicism — Diving into the promises and challenges of characterizing clonal hematopoiesis of indeterminate potential

Ross Levine, MD; Kelly Bolton, MD, PhD; Jyoti Nangalia, MD, PhD; Todd Druley, MD, PhD

poster

Enabling single cell analysis of copy number variation in breast cancer

Jacqueline Marin

AACR (2022)

poster

Linking phenotype and genotype: multimodal analysis of surface proteins, intracellular proteins, and SNVs in single cells

Aik Ooi

AACR (2022)

publication

scTAM-seq enables targeted high-confidence analysis of DNA methylation in single cells

Bianchi A et al.

BioRxiv (2022)

publication

Single-cell analysis reveals selection of TP53-mutated clones after MDM2 inhibition

Maslah N et al.

Blood Advances (2022)

publication

Monitoring of leukemia clones in B-cell acute lymphoblastic leukemia at diagnosis and during treatment by single-cell DNA amplicon sequencing

Meyers S et al.

HemaSphere (2022)

publication

Clonal hematopoiesis, myeloid disorders and BAX-mutated myelopoiesis in patients receiving venetoclax for CLL

Blombery P et al.

Blood (2022)

publication

Developmental venous anomalies are a genetic primer for cerebral cavernous malformations

Snellings D.A. et al.

Nature (2022)

publication

Application of high-throughput, high-depth, targeted single-nucleus DNA sequencing in pancreatic cancer

Zhang H et al.

BioRxiv (2022)

publication

Mechanisms of resistance to noncovalent Bruton's tyrosine kinase inhibitors

Wang E et al.

New England Journal of Medicine (2022)

publication

Reconstructing mutational lineages in breast cancer by multi-patient-targeted single cell DNA sequencing

Leighton J et al.

BioRxiv (2022)

publication

Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

Zhang Q et al.

Nature (2022)

Scientific Presentation

Meet the Authors: Clonal Heterogeneity in Acute Lymphoblastic Leukemia at Diagnosis and During Chemo Treatment

Jan Cools, PhD, VIB Center for Cancer Biology

publication

Preneoplastic somatic mutations including MYD88L265P in lymphoplasmacytic lymphoma

Rodriguez S et al.

Science Advances (2022)

publication

Molecular characterization of acquired resistance to KRAS G12C inhibition in gastrointestinal cancers

Misale S et al.

Research Square (2022)

publication

Single-cell sequencing demonstrates complex resistance landscape in CLL and MCL treated with BTK and BCL2 inhibitors

Thompson ER et al.

Blood Advances (2021)

brochure

Mission Bio Publication List

FLYER

video

Mission Bio CEO Talks Single Cell at Cell & Gene Meeting on the Mesa