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Publications

Clonal Evolution and Changes in Two AML Patients Detected with A Novel Single-Cell DNA Sequencing Platform

Xu, L. et. al., Scientific Reports (2019)
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Publications

Polyclonal Heterogeneity: The New Norm for Secondary Clinical Resistance to Targeted Monotherapy in Relapsed Leukemia?

Wei, A. et. al., Cancer Discovery (2019)
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Publications

V211D mutation in MEK1 causes resistance to MEK inhibitors in colon cancer

Gao, Y. et. al., Cancer Discovery (2019)
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Publications

Clonal selection with Ras pathway activation mediates secondary clinical resistance to selective FLT3 inhibition in acute myeloid leukemia

McMahon, C. et. al., Cancer Discovery (2019)
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Publications

High-throughput single-cell DNA sequencing of acute myeloid leukemia tumors with droplet microfluidics

Eastburn, D. et. al., Genome Research (2018)
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Publications

Differential roles for Lgr5 and Lgr6 in epidermal stem cell lineage selection and squamous tumour development.

Huang, P., et. al., Nature Genetics (2017)
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Publications

Microfluidic droplet enrichment for targeted sequencing.

Eastburn, D. et. al., Nucleic Acids Research (2015)
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Publications

RNASeq following PCR-based sorting reveals rare cell transcriptional signatures.

Pellegrino, M., et. al., BMC Genomics (2016)
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Publications

Identification and genetic analysis of cancer cells with PCR-activated cell sorting.

Eastburn, D., et al., Nucleic Acids Research (2014)
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Scientific Presentations

Get SNVs and CNVs from the Tapestri Platform


Kelly Kaihara, PhD,
Market Development, Mission Bio

Robert Durruthy-Durruthy, PhD,
Support Team, Mission Bio
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Scientific Presentations

Single-Cell Sequencing Reveals Clonal Heterogeneity in Acute Lymphoblastic Leukemia


Jan Cools, Professor Genetics KU Leuven, Group Leader VIB, Leuven, Belgium

Llucia Albertí Servera, Postdoctoral Researcher, VIB-KU Leuven, Belgium

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Scientific Presentations

Single-Cell Genomics Provides New Insights Into the Heterogeneity of CLL and AML


Koichi Takahashi, MD, University of Texas MD Anderson Cancer Center

Esteban Braggio, PhD, Mayo Clinic Arizona
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Scientific Presentations

Profiling clonal hematopoiesis in cancer survivors with single-cell DNA sequencing


Dr. Chuck Gawad, MD, PhD
St. Jude Children's Research Hospital
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Scientific Presentations

Precision Sequencing with Single-Cell Genomics: Resolving Heterogeneity in Blood and Solid Tumors


Dennis Eastburn, CSO
Mission Bio

Jerry Radich, Professor
University of Washington
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Scientific Presentations

The Next Era in Single-Cell Genomics and Precision Medicine


Dennis Eastburn, CSO
Mission Bio

Catherine Smith, MD

Aaron Viny, MD MS
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Scientific Presentations

High-throughput Single Cell DNA Sequencing of Acute Myeloid Leukemia Tumors by Droplet Microfluidics


Koichi Takahashi, MD, University of Texas MD Anderson Cancer Center
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Scientific Presentations

Single-Cell DNA Analysis: Resolving Tumor Heterogeneity with Implications for Dynamic Therapy


Alexander Pearl
University of Pennsylvania

Catherine Smith
Collaborator from UCSF
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Scientific Presentations

Unlocking the Power of Single-Cell DNA Analysis with Simple Software


Anup Parikh, PhD,
Mission Bio
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Scientific Presentations

Precision Over Bulk

Opportunities for Single Cell DNA Analysis in Oncology
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Researcher Spotlights

Ravi Majet, MD, PhD

Transforming the Detection of Minimal Residual Disease (MRD) with Single-Cell DNA Analysis
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Researcher Spotlights

Catherine Smith, MD

Beyond Bulk Sequencing: Single-Cell DNA Analysis in Cancer Research and the Potential of Dynamic Therapy
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Videos

Data Analysis and Software Solutions - Mission Bio and BlueBee


Anup Parikh, PhD
Mission Bio
Mike Kubal
BlueBee
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Videos

Learn More with Tapestri


Jerry Radich, MD
Fred Hutchinson Cancer Center
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Videos

Tapestri Designer Portal Video


An instructive, visual tour through Tapestri Designer

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Videos

TechEdge Tapestri Video


A brief introduction to the innovative technology, benefits, and applications of Tapestri platform
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Videos

Meet Mission Bio

Moving Precision Medicine Forward
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Videos

Meet Tapestri

Novel Droplet Microfluidics for Single-Cell DNA Analysis
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Videos

Meet Tapestri Insights

Intuitive Software to Resolve Your Complex Clonal Questions
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Brochures

Mission Bio Tapestri® Platform

Clonal Diversity Revealed
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Brochures

Tapestri Single-Cell DNA Custom Panels

The only customizable single-cell DNA targeted solution for high impact applications
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Brochures

Platform Brochure
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Brochures

Tapestri Single-Cell DNA Catalog Panels
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Data Sets

4 cell line mix for CNV and SNV Analysis

Sample dataset for a 4-cell line mixed experiment using the Tapestri Single-Cell DNA AML_v2 panel

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Data Sets

AML Catalog Panel

Sample dataset for the Tapestri Single Cell DNA AML panel
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Data Sets

Myeloid Catalog Panel

Sample dataset for the Tapestri Single Cell DNA Myeloid panel
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Data Sets

CLL Catalog Panel

Sample dataset for the Tapestri Single Cell DNA CLL panel
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Data Sets

50:50 Mix for CNV and SNV Analysis

Sample dataset for a KG-1:Raji cell lines 50:50 mix experiment using the Tapestri Single-Cell DNA Myeloid panel
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Data Sets

4 Cell Line Mix

Sample dataset for a 4-cell line mixed experiment using the Tapestri Single-Cell DNA AML panel
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User Guide

Tapestri Single-Cell DNA Sequencing V2 User Guide
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Quick Reference Card

Targted Single-Cell DNA Sequencing using the Tapestri Platform V2 Quick Reference Card
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Site Requirements

Tapestri Instrument Site Requirements
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User Guide

Tapestri Instrument User Guide
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User Guide

Nuclei Extraction From Frozen Tissue For Single-Nuclei DNA Sequencing
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Application Note

Protein Application Note
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Application Note

CNV Application Note
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Application Note

MDS Application Note
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White Paper

Performance of the Tapestri® Platform for Single-Cell Targeted DNA Sequencing
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Application Note

CLL Application Note
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Application Note

Solid Tumor Application Note
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Application Note

Quality Control of CRISPR edits with Tapestri
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Posters

Error correction in single-cell DNA sequencing: finding rare allele for MRD clone

SCG 2019
Dong Kim, MS
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Posters

Doublets detection in single-cell DNA-sequencing using deep learning

SCG 2019
Sombeet Sahu, MS
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Posters

Using machinge learning to optimize assays for single-cell targeted DNA sequencing

SCG 2019
Shu Wang, PhD
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Posters

High-throughput single-cell targted DNA sequencing for hematologic cancers using droplet-based microfluidic platform

SOHO 2019
Benchun Liu, PhD
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Posters

An automated high-throughput custom single-cell targeted DNA sequencing platform to reveal rare clonal evolution in cancer and characterize mutation profiles in CRISPR edited cells

ASHG 2019
Daniel Mendoza, PhD
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Posters

Single-cell Simultaneous Detection of DNA Genotype and Protein Expression

SCG 2019
Aik Ooi PhD
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Posters

Highly robust and sensitive off-the-shelf and custom cancer solutions for high-throughput single-cell targted DNA sequencing

AGBT 2019
Kathryn Thompson
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Posters

Co-detection of mutations and copy number variations in thousands of single-cells using an automated platform

SCG 2019
Adam Sciambi, PhD
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Posters

Single-cell multi-omics for simultaneous detection of SNVs, CNVs and proteins using the Tapestri Platform

AMP 2019
Aik Ooi, PhD
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Posters

Analytical methods to identify tumor heterogeneity and rare subclones in single-cell DNA sequencing data from targeted panels

AACR 2019
Manimozhi Manivannan, PhD
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Posters

Methods to detect large indels and tandem duplication in Acute Myeloid Leukemia using single-cell DNA sequencing

ISMB 2019
Sombeet Sahu, MS
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Posters

High-throughput single-cell targeted DNA sequencing from frozen, fixed and preserved solid tumor samples reveals complex genomic variation and clonal propagation

AACR 2019
Pedro Mendez, PhD
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Posters

Analytical methods to identify tumor heterogeneity and rare subclones in single-cell DNA sequencing data from targeted panels

ISMB 2019
Sombeet Sahu, MS
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Posters

High-throughput single-cell targeted DNA sequencing using an updated Tapestri Platform reveals rare clones and clonal evolution for multiple blood cancers

AACR 2019
Nianzhen Li, PhD