Clonal evolution and changes in two AML patients detected with a novel single-cell DNA sequencing platform
Xu, L. et. al., Scientific Reports (2019)
Polyclonal heterogeneity: the new norm for secondary clinical resistance to targeted monotherapy in relapsed leukemia?
Wei, A. et. al., Cancer Discovery (2019)
V211D mutation in MEK1 causes resistance to MEK inhibitors in colon cancer
Gao, Y. et. al., Cancer Discovery (2019)
Clonal selection with Ras pathway activation mediates secondary clinical resistance to selective FLT3 inhibition in acute myeloid leukemia
McMahon, C. et. al., Cancer Discovery (2019)
High-throughput single-cell DNA sequencing of acute myeloid leukemia tumors with droplet microfluidics
Eastburn, D. et. al., Genome Research (2018)
Differential roles for Lgr5 and Lgr6 in epidermal stem cell lineage selection and squamous tumour development.
Huang, P., et. al., Nature Genetics (2017)
Microfluidic droplet enrichment for targeted sequencing.
Eastburn, D. et. al., Nucleic Acids Research (2015)
RNA-Seq following PCR-based sorting reveals rare cell transcriptional signatures.
Pellegrino, M., et. al., BMC Genomics (2016)
Identification and genetic analysis of cancer cells with PCR-activated cell sorting.
Eastburn, D., et al., Nucleic Acids Research (2014)
In pursuit of the leukemic stem cell: leveraging single cell genomics and proteomics to identify drivers of AML
Katherine D Cummins, MD, FRACP, FRCPA,Lab of Saar Gill,MD, PhD,University of Pennsylvania
Investigation of AML clonal architecture with mutational and immunophenotypic profiling simultaneously from the same cell(s)
Linde Miles, PhD,Lab of Ross L. Levine, MD,Memorial Sloan Kettering Cancer Center
Get SNVs and CNVs from the Tapestri Platform
Kelly Kaihara, PhDMission BioRobert Durruthy-Durruthy, PhDMission Bio
Single-Cell Sequencing Reveals Clonal Heterogeneity in Acute Lymphoblastic Leukemia
Jan Cools, PhDVIBLlucia Alberti Servera, PhDVIB
High-throughput Single Cell DNA Sequencing of Acute Myeloid Leukemia Tumors by Droplet Microfluidics
Koichi Takahashi, MDMD Anderson Cancer Center
Single-Cell Genomics Provides New Insights Into the Heterogeneity of CLL and AML
Koichi Takahashi, MDMD Anderson Cancer CenterEsteban Braggio, PhDMayo Clinic, Arizona
Profiling clonal hematopoiesis in cancer survivors with single-cell DNA sequencing
Chuck Gawad, MD, PhDSt. Jude’s Children’s Research Hospital
Precision Sequencing with Single-Cell Genomics: Resolving Heterogeneity in Blood and Solid Tumors
Dennis Eastburn, CSOMission BioJerry Radich, MDUniversity of Washington
The Next Era in Single-Cell Genomics and Precision Medicine
Dennis Eastburn, CSOMission BioCatherine Smith, MDUCSFAaron Viny, MD MSMemorial Sloan Kettering Cancer Center
Single-Cell DNA Analysis: Resolving Tumor Heterogeneity with Implications for Dynamic Therapy
Alexander Pearl, MD MSUniversity of PennsylvaniaCatherine Smith, MDUCSF
Unlocking the Power of Single-Cell DNA Analysis with Simple Software
Anup Parikh, PhDMission Bio
Precision Over Bulk
Koichi Takahashi, MDMD Anderson Cancer CenterDennis Eastburn, CSOMission BioJerry Radich, MDUniversity of Washington
Ravi Majeti, MD, PhD
Transforming the detection of minimal residual disease (MRD) with single-cell DNA analysis
Catherine Smith, MD
Beyond bulk sequencing: single-cell DNA analysis in cancer research and the potential of dynamic therapy
Data Analysis and Software Solutions - Mission Bio and BlueBee
Anup Parikh, PhD Mission BioMike KubalBlueBee
Learn More with Tapestri
Jerry Radich, MD Fred Hutchinson Cancer Center
Tapestri Designer Portal Video
An instructive, visual tour through Tapestri Designer
TechEdge Tapestri Video
A brief introduction to the innovative technology, benefits, and applications of Tapestri platform
Meet Mission Bio
Moving Precision Medicine Forward
Meet Tapestri
Novel Droplet Microfluidics for Single-Cell DNA Analysis
Meet Tapestri Insights
Intuitive Software to Resolve Your Complex Clonal Questions
Tapestri® Platform Brochure
Mission Bio Tapestri® Platform
Tapestri® Single-Cell DNA Panels
Tapestri® Single-Cell DNA Custom Panels
AML Catalog Panel
Sample dataset for the Tapestri Single Cell DNA AML panel
Myeloid Catalog Panel
Sample dataset for the Tapestri Single Cell DNA Myeloid panel
CLL Catalog Panel
Sample dataset for the Tapestri Single Cell DNA CLL panel
4 Cell Line Mix
Sample dataset for a 4-cell line mixed experiment using the Tapestri Single-Cell DNA AML panel
4 cell line mix for CNV and SNV Analysis
Sample dataset for a 4-cell line mixed experiment using the Tapestri Single-Cell DNA AML_v2 panel
50:50 Mix for CNV and SNV Analysis
Sample dataset for a KG-1:Raji cell lines 50:50 mix experiment using the Tapestri Single-Cell DNA Myeloid panel
Tapestri Single-Cell DNA Sequencing V2 User Guide
Targted Single-Cell DNA Sequencing using the Tapestri Platform V2 Quick Reference Card
Tapestri Instrument Site Requirements
Tapestri Instrument User Guide
Nuclei Extraction From Frozen Tissue For Single-Nuclei DNA Sequencing
Protein Application Note
CNV Application Note
MDS Application Note
Performance of the Tapestri® Platform for Single-Cell Targeted DNA Sequencing
CLL Application Note
Solid Tumor Application Note
Quality Control of CRISPR edits with Tapestri
Single-cell multi-omics for simultaneous detection of SNVs, CNVs and proteins using the Tapestri Platform
AMP 2019Aik Ooi, PhD
An automated high-throughput custom single-cell targeted DNA sequencing platform to reveal rare clonal evolution in cancer and characterize mutation profiles in CRISPR edited cells
ASHG 2019Daniel Mendoza, PhD
High-throughput single-cell targted DNA sequencing for hematologic cancers using droplet-based microfluidic platform
SOHO 2019Benchun Liu, PhD
Using machinge learning to optimize assays for single-cell targeted DNA sequencing
SCG 2019Shu Wang, PhD
Co-detection of mutations and copy number variations in thousands of single-cells using an automated platform
SCG 2019Adam Sciambi, PhD
Doublets detection in single-cell DNA-sequencing using deep learning
SCG 2019Sombeet Sahu, MS
Single-cell Simultaneous Detection of DNA Genotype and Protein Expression
SCG 2019Aik Ooi, PhD
Error correction in single-cell DNA sequencing: finding rare allele for MRD clone
SCG 2019Dong Kim, MS
Highly robust and sensitive off-the-shelf and custom cancer solutions for high-throughput single-cell targted DNA sequencing
AGBT 2019Kathryn Thompson
Analytical methods to identify tumor heterogeneity and rare subclones in single-cell DNA sequencing data from targeted panels
ISMB 2019Sombeet Sahu, MS
Methods to detect large indels and tandem duplication in Acute Myeloid Leukemia using single-cell DNA sequencing
High-throughput single-cell targeted DNA sequencing from frozen, fixed and preserved solid tumor samples reveals complex genomic variation and clonal propagation
AACR 2019Pedro Mendez, PhD
AACR 2019Manimozhi Manivannan, PhD
High-throughput single-cell targeted DNA sequencing using an updated Tapestri Platform reveals rare clones and clonal evolution for multiple blood cancers
AACR 2019Nianzhen Li, PhD
