While the development of small molecules and proteins have driven therapeutic benefits, the next generation of cell and gene therapies holds tremendous promise for patients. With a precise single-cell picture, you can optimize transduction efficiency, understand the complexity of genome edits, and better characterize your cell and gene therapy candidate. Perform more comprehensive assay characterization to accelerate approvals and go to market faster.
TALK TO A SCIENTISTWhether it is genome-editing systems or viral vector systems, single-cell analysis uncovers the changes that are made to the DNA from thousands of single cells per sample. Uncover the clonality within the sample after editing protocols have been executed, and verifify what percentage of the cells have the desired DNA edits or insertions. Use a custom single-cell DNA panel designed with Tapestri Designer to measure zygosity, co-occurrence of multiple edits, on and predicted off-target events, aberrant translocations, and viral and/or DNA integration. Use single-cell information for the rapid optimization of genome editing of viral/DNA integration protocls during therapy development and streamlined testing and release of edited or integrated cells during manufacturing of therapeutic products.
It is time to stop developing therapies in the dark
Elisa ten Hacken, Ph.D., Dana Farber Cancer Institute
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Custom designs with Tapestri DesignerTo support the development and quality control of your cell and gene therapy programs, we provide full service as a strategic partner for you from study design, assay design, sample processing, through to data analysis and interpretation. Whether we offer services internally or in partnership with qualified CROs, we are dedicated to the accelerated success of your cell and gene therapies.