Tapestri Single-cell DNA Acute Lymphoblastic Leukemia Panels
Acute lymphoblastic leukemia (ALL) is the most common type of cancer in children, which like other cancers is caused by complex genetic mutations. As this complex disease evolves, understanding genetic variability — including mutation co-occurrence at the single-cell level — is vitally important in order for clinical researchers to break the cycle of treatment response, resistance and relapse.
Advance your understanding of the genetic heterogeneity underpinning acute lymphoblastic leukemia (ALL) by targeting 107 genes with 283 amplicons for single-cell sequencing. Incorporating a combination of oncogenes and tumor suppressor genes, this panel is designed to cover some of the most commonly mutated genes associated with ALL.
Single-cell Sequencing Reveals Clonal Heterogeneity in Acute Lymphoblastic Leukemia.
Jan Cools, professor Genetics KU Leuven, group leader VIB, Leuven, Belgium
Llucia Albertí Servera, postdoctoral Researcher, VIB-KU Leuven, Belgium
Unraveling Clonal Heterogeneity and Evolutionary History of Acute Myeloid Leukemia by Single-cell DNA Sequencing.
Koichi Takahashi, MD, University of Texas MD Anderson Cancer Center