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Profile

Nicholas E. Navin, PhD

Dr. Nicholas Navin is a tenured associate professor in the Department of Genetics and the Department of Bioinformatics and Computational Biology at the MD Anderson Cancer Center. He is the director of the CPRIT Single Cell Genomics Center and co-director of the Advanced Genomic Technology Center (AGTC). He is also the co-leader of the Human Breast Cell Atlas Project. Dr. Navin completed his Ph.D. and postdoctoral studies at the Cold Spring Harbor Laboratory and Stony Brook University. Dr. Navin is internationally recognized for his seminal work on developing single-cell DNA sequencing techniques to study cancer. Dr. Navin developed the first single-cell DNA sequencing method (Navin et al. 2011 Nature), which played a pivotal role in establishing the field of single-cell genomics. His research work focuses on understanding clonal evolution in cancer in the context of invasion, metastasis, and therapy resistance. His research group has identified a punctuated model of copy number evolution in breast cancer, multi-clonal invasion in DCIS breast cancer, and transcriptional reprogramming during chemotherapy resistance in triple-negative disease. Dr. Navin has been the recipient of many prestigious awards, including the AAAS Wachtel Award, the ACS Research Scholar Award, the Living Legend Basic Science Award, the Damon-Runyon Innovator Award, and he was a Finalist for the 2019 Blavatnik Award.



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