Publications

Mission Bio Resource

Polyclonal Heterogeneity: The New Norm for Secondary Clinical Resistance to Targeted Monotherapy in Relapsed Leukemia?

Wei, A. et. al., Cancer Discovery (2019)

Mission Bio Resource

Clonal Evolution and Changes in Two AML Patients Detected with A Novel Single-Cell DNA Sequencing Platform

Xu, L. et. al., Scientific Reports (2019)

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V211D mutation in MEK1 causes resistance to MEK inhibitors in colon cancer

Gao, Y. et. al., Cancer Discovery (2019)

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Clonal selection with Ras pathway activation mediates secondary clinical resistance to selective FLT3 inhibition in acute myeloid leukemia

McMahon, C. et. al., Cancer Discovery (2019)

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High-throughput single-cell DNA sequencing of acute myeloid leukemia tumors with droplet microfluidics

Eastburn, D. et. al., Genome Research (2018)

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Differential roles for Lgr5 and Lgr6 in epidermal stem cell lineage selection and squamous tumour development.

Huang, P., et. al., Nature Genetics (2017)

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RNASeq following PCR-based sorting reveals rare cell transcriptional signatures.

Pellegrino, M., et. al., BMC Genomics (2016)

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Microfluidic droplet enrichment for targeted sequencing.

Eastburn, D. et. al., Nucleic Acids Research (2015)

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Identification and genetic analysis of cancer cells with PCR-activated cell sorting.

Eastburn, D., et al., Nucleic Acids Research (2014)

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Scientific Presentations

Mission Bio Resource

Single-Cell Sequencing Reveals Clonal Heterogeneity in Acute Lymphoblastic Leukemia

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Get SNVs and CNVs from the Tapestri Platform

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Single-Cell Genomics Provides New Insights Into the Heterogeneity of CLL and AML

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High-throughput Single Cell DNA Sequencing of Acute Myeloid Leukemia Tumors by Droplet Microfluidics

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Unlocking the Power of Single-Cell DNA Analysis with Simple Software

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Single-Cell DNA Analysis: Resolving Tumor Heterogeneity with Implications for Dynamic Therapy

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Profiling clonal hematopoiesis in cancer survivors with single-cell DNA sequencing

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Precision Sequencing with Single-Cell Genomics: Resolving Heterogeneity in Blood and Solid Tumors

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The Next Era in Single-Cell Genomics and Precision Medicine

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Precision Over Bulk

Opportunities for Single Cell DNA Analysis in Oncology

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Researcher Spotlights

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Ravi Majet, MD, PhD

Transforming the Detection of Minimal Residual Disease (MRD) with Single-Cell DNA Analysis

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Catherine Smith, MD

Beyond Bulk Sequencing: Single-Cell DNA Analysis in Cancer Research and the Potential of Dynamic Therapy

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Videos

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Data Analysis and Software Solutions - Mission Bio and BlueBee

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Learn More with Tapestri

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Tapestri Designer Portal Video

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TechEdge Tapestri Video

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Meet Mission Bio

Moving Precision Medicine Forward

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Meet Tapestri

Novel Droplet Microfluidics for Single-Cell DNA Analysis

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Meet Tapestri Insights

Intuitive Software to Resolve Your Complex Clonal Questions

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Brochures

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Mission Bio Tapestri® Platform

Clonal Diversity Revealed

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Tapestri Single-Cell DNA Custom Panels

The only customizable single-cell DNA targeted solution for high impact applications

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Platform Brochure

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Tapestri Single-Cell DNA Catalog Panels

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Data Sets

Data should be loaded in the Tapestri Insights software for cell and variant filtering and subclone analysis.

User Guides

Application / Technical Notes

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Protein Application Note

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CNV Application Note

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Performance of the Tapestri® Platform for Single-Cell Targeted DNA Sequencing

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MDS Application Note

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CLL Application Note

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Solid Tumor Application Note

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Quality Control of CRISPR edits with Tapestri

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