Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
X
X
publication

A JAK2/IDH1-mutant MPN clone unmasked by ivosidenib in an AML patient without antecedent MPN


Xiao, W. et al.
Blood Advances (2020)
Abstract

  • Myeloid neoplasm (MPN) clones can evolve from acute myeloid leukemia to gain dominance with isocitrate dehydrogenase inhibition.
  • Pro-differentiation agents such as ivosidenib can unmask MPN sequelae.



Authors

Xiao, W., Miles, L.A.., Bowman R.L., Durani, V., Tian H.S., DelGaudio, N.L., Mishra, T., Zhu, M. Zhang, Y., Stump, S.E.., Tallman, M.S., Levine, R.L.., Cai, S.F.



VIEW

publication
Impact of Clonal Architecture on Clinical Course and Prognosis in Patients With Myeloproliferative Neoplasms
Luque Paz, Damien
HemaSphere
publication
Massively parallel base editing to map variant effects in human hematopoiesis
Jorge D. Martin-Rufino
Cell
publication
Spectrum of clonal hematopoiesis in VEXAS syndrome
Fernanda Gutierrez-Rodrigues
Blood
publication
Detection and targeting of splicing deregulation in pediatric acute myeloid leukemia stem cells
Inge van der Werf
Cell Reports Medicine
REQUEST QUOTE