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Events

Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms

VIRTUAL
Zoom meeting
August 4, 2020

Challenging the dogma that mutations in RNA splicing factors do not occur in the same cell, due to their synthetic lethal interactions and/or convergent effects, Dr. Justin Taylor from the Abdel-Wahab lab at Memorial Sloan Kettering Cancer Center show that indeed they can. Using Mission Bio’s single-cell sequencing platform, they sequenced closed to 100,000 single cells, and found instances in which mutations in splicing factors co-occurred within the same cells. Come join us as Dr. Taylor explains these exciting new data from his recent Blood publication that just came out in July 2020.

DATE & TIME
08.04.2020
9:30AM
LOCATION
Zoom meeting
PUBLICATION
NUMBER
PRESENTERS
Justin Taylor, MD
SESSION
RNA splicing factors do not occur in the same cell, due to their synthetic lethal interactions and/or convergent effects.

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