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ebook

Single-cell Sequencing 101: DNA & multi-omics for precision medicine

Abstract

Cancer is a complex disease that continuously evolves in response to environmental pressures. The dynamism and heterogeneity of tumors have significant clinical implications. In this eBook, review how single-cell DNA sequencing and multi-omics are used to dissect clonal architecture, providing valuable insights for clinical strategies, disease modeling, and the development of cell and gene therapies.

Specifically, we cover:

  • The clonal evolution of cancer
  • Linking genotype & phenotype with multi-omics
  • Translational applications for the clinic
  • Single-cell analysis of genome engineering


Technical Note
Assessment of Whole-Genome Copy Number Variation with Tapestri Single-Cell Analysis
Technical Note
Beyond basic characterization: the synergistic power of Tapestri and patient-derived xenografts to accelerate drug discovery
Technical Note
High-throughput assessment of genome edited cells with Tapestri antibody hashing
Technical Note
Unprecedented Resolution of Genome Editing Outcomes with Single-cell Analysis
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