poster

Analytical methods to identify tumor heterogeneity and rare subclones in single-cell DNA sequencing data from targeted panels

Manimozhi Manivannan

High-throughput single-cell DNA sequencing is essential to assess genetic variations in rare cells and better understand the role they play in the evolution of tumor progression. To address these challenges and enable the characterization of genetic diversity in cancer cell populations, we developed a novel approach to identify mutation signatures, which define subclones present in tumor populations.

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poster

Single-cell Multiomic Clonal Tracking in Myeloma Identifies SMM Clones that Progress to MM and Low-Frequency MM Clones with Resistance Features Enabling More Precise Application of Targeted Therapies

Adam Sciambi

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A novel single-cell measurable residual disease (scMRD) assay for simultaneous DNA mutation and surface immunophenotype profiling

Holly Tillson

poster

Single-cell multiomic clonal tracking in myeloma identifies SMM clones that progress to MM and low frequency MM clones with resistance features enabling more precise application of targeted therapies.

Adam Sciambi

poster

High Throughput Single Cell Analysis Workflow for Accurate Measurement of Genotoxicity Arising from Gene Editing Experiments

Saurabh Gulati

Analytical methods to identify tumor heterogeneity and rare subclones in single-cell DNA sequencing data from targeted panels

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