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Announcing the new Tapestri Solution for Solid Tumor Oncology Research. Learn More
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Analytical methods to identify tumor heterogeneity and rare subclones in single-cell DNA sequencing data from targeted panels


Manimozhi Manivannan

High-throughput single-cell DNA sequencing is essential to assess genetic variations in rare cells and better understand the role they play in the evolution of tumor progression. To address these challenges and enable the characterization of genetic diversity in cancer cell populations, we developed a novel approach to identify mutation signatures, which define subclones present in tumor populations.


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Leveraging Single-cell DNA Sequencing for In-depth Characterization of Cell and Gene Therapies
Jacqueline Marin, Benjamin Schroeder, Shu Wang, Daniel Mendoza, Adam Sciambi, Brittany Enzmann
poster
Multimodal Analysis of DNA and Proteins in Single Cells
Prithvi Singh, Dalia Dhingra, Saurabh Parikh, Adam Sciambi, Aik Ooi
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Precise Measurement of Transduction Efficiency at Single-Cell Resolution for Cell and Gene Therapy Development
Khushali Patel
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Enabling single cell analysis of copy number variation in breast cancer
Jacqueline Marin
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