Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
X
Announcing the new Tapestri Solution for Solid Tumor Oncology Research. Learn More
X
poster

Single-cell multi-omics for simultaneous detection of SNVs, CNVs, and proteins using the Tapestri Platform


Aik Ooi, PhD

Genomics data alone provides only partial insights into the cell’s type, state, or function. To obtain a more complete picture and reveal the cell’s phenotypic character, a multi-omics approach is needed that expands beyond DNA profiling. Here, we demonstrate for the first time, that the Tapestri Platform enables the detection of genomic variants and protein expression simultaneously from the same cell. Genomic variations, such as single nucleotide variants (SNVs) and copy number variations (CNVs), are now co-detected with proteins. This novel capability has the power to reveal rare cell populations, subtle cell states, and link genomic variation to protein expression, leading to more informed research on disease and therapeutic development.


VIEW
poster
Leveraging Single-cell DNA Sequencing for In-depth Characterization of Cell and Gene Therapies
Jacqueline Marin, Benjamin Schroeder, Shu Wang, Daniel Mendoza, Adam Sciambi, Brittany Enzmann
poster
Multimodal Analysis of DNA and Proteins in Single Cells
Prithvi Singh, Dalia Dhingra, Saurabh Parikh, Adam Sciambi, Aik Ooi
poster
Precise Measurement of Transduction Efficiency at Single-Cell Resolution for Cell and Gene Therapy Development
Khushali Patel
poster
Enabling single cell analysis of copy number variation in breast cancer
Jacqueline Marin
REQUEST QUOTE