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poster

An automated high-throughput custom single-cell targeted DNA sequencing platform to reveal rare clonal evolution in cancer and characterize mutation profiles in CRISPR edited cells


Daniel Mendoza
ASHG (2019)

Many stages of hematopoietic differentiation provide multiple opportunities for mutations that lead to distinct tumor subtypes. However, standard bulk population sequencing is hard to identify rare alleles or determine whether multiple mutations co-occur within the same cell.


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poster
Amplicon design algorithm for single cell targeted DNA sequencing using machine learning
Shu Wang
AACR (2020)
poster
Improvements in variant calling sensitivity and specificity in single-cell DNA sequencing using deep learning
Manimozhi Manivannan
AACR (2020)
poster
Powerful insights with single-cell multi-omics: Co-detecting both genotype and phenotype from the same cell
James Flynn, PhD
AGBT (2020)
poster
Subclonal identification of driver mutations and copy number variations from single-cell DNA sequencing of tumors
James Flynn, PhD
ABRF (2020)
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