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Analytical methods to identify tumor heterogeneity and rare subclones in single-cell DNA sequencing data from targeted panels

Sombeet Sahu, MS

It is essential to develop new capabilities for assessing genetic variation present in rare cells and to better understand the role that these cells play in the evolution of tumor progression. With the advancement of single-cell sequencing technologies, it is now possible to interrogate thousands of cells in a single experiment.

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Single-cell Multiomic Clonal Tracking in Myeloma Identifies SMM Clones that Progress to MM and Low-Frequency MM Clones with Resistance Features Enabling More Precise Application of Targeted Therapies

Adam Sciambi

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A novel single-cell measurable residual disease (scMRD) assay for simultaneous DNA mutation and surface immunophenotype profiling

Holly Tillson

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Single-cell multiomic clonal tracking in myeloma identifies SMM clones that progress to MM and low frequency MM clones with resistance features enabling more precise application of targeted therapies.

Adam Sciambi

poster

High Throughput Single Cell Analysis Workflow for Accurate Measurement of Genotoxicity Arising from Gene Editing Experiments

Saurabh Gulati

Analytical methods to identify tumor heterogeneity and rare subclones in single-cell DNA sequencing data from targeted panels

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