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An automated high-throughput custom single-cell targeted DNA sequencing platform to reveal rare clonal evolution in cancer and characterize mutation profiles in CRISPR edited cells

Adam Sciambi

Understanding tumor heterogeneity and clonal evolution has major implications in oncology research. Both chromosomal structural change/copy number alteration/variation (CNA/CNV) and driver gene mutation events are critical in cancer initiation and progression.

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poster

Single-cell Multiomic Clonal Tracking in Myeloma Identifies SMM Clones that Progress to MM and Low-Frequency MM Clones with Resistance Features Enabling More Precise Application of Targeted Therapies

Adam Sciambi

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A novel single-cell measurable residual disease (scMRD) assay for simultaneous DNA mutation and surface immunophenotype profiling

Holly Tillson

poster

Single-cell multiomic clonal tracking in myeloma identifies SMM clones that progress to MM and low frequency MM clones with resistance features enabling more precise application of targeted therapies.

Adam Sciambi

poster

High Throughput Single Cell Analysis Workflow for Accurate Measurement of Genotoxicity Arising from Gene Editing Experiments

Saurabh Gulati

An automated high-throughput custom single-cell targeted DNA sequencing platform to reveal rare clonal evolution in cancer and characterize mutation profiles in CRISPR edited cells

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