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poster

An automated high-throughput custom single-cell targeted DNA sequencing platform to reveal rare clonal evolution in cancer and characterize mutation profiles in CRISPR edited cells


Adam Sciambi
SCG (2019)

Understanding tumor heterogeneity and clonal evolution has major implications in oncology research. Both chromosomal structural change/copy number alteration/variation (CNA/CNV) and driver gene mutation events are critical in cancer initiation and progression.


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poster
Amplicon design algorithm for single cell targeted DNA sequencing using machine learning
Shu Wang
AACR (2020)
poster
Improvements in variant calling sensitivity and specificity in single-cell DNA sequencing using deep learning
Manimozhi Manivannan
AACR (2020)
poster
Powerful insights with single-cell multi-omics: Co-detecting both genotype and phenotype from the same cell
James Flynn, PhD
AGBT (2020)
poster
Subclonal identification of driver mutations and copy number variations from single-cell DNA sequencing of tumors
James Flynn, PhD
ABRF (2020)
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