Home Resources Presentations Longitudinal analysis reveals pre-existing resistant clones

FILTER RESOURCES

ALL FEATURED PUBLICATIONS SCIENTIFIC PRESENTATIONS RESEARCHER SPOTLIGHTS VIDEOS BROCHURES DATASETS USER GUIDES TECHNICAL NOTES POSTERS EBOOKS

Scientific presentation

Longitudinal analysis reveals pre-existing resistant clones

Catherine Smith, MD

Description

Dr. Cathy Smith from UCSF provides a case study on single-cell sequencing of polyclonal resistance to FLT3 inhibitors in acute myeloid leukemia (AML). She presents data taken over a period of 28, 48, and 92 days to reveal that NRAS clones were detectable in 0.1% of cells with single-cell analysis at 28 days, which was previously undetectable with bulk sequencing until relapse.

Scientific presentation

Getting Started with Single-cell DNA Sequencing Series: Fundamentals & Wet Lab Needs

Rachel Agoglia, PhD

Scientific presentation

From Stealth to Spotlight: Single-Cell Identification of SMM Clones Driving Myeloma Progression and Therapy Resistance

Adam Sciambi, PhD

Scientific presentation

Multiplexing 101: Unlocking Critical Single-Cell Insights with Increased Throughput and Efficiency

Jacqueline Marin

Scientific presentation

Single-cell Multi-omics for Discovery, Translational, and Clinical Development

Gema Fuerte, PhD

World CDx Europe (2024)

REQUEST QUOTE