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Announcing the new Tapestri Solution for Solid Tumor Oncology Research. Learn More
Scientific presentation

Precision sequencing with single-cell genomics: resolving heterogeneity in blood and solid tumors

Dennis Eastburn, PhD

The Tapestri Platform provides a single-cell DNA sequencing approach to understand clonal architecture and disease progression. By using microfluidics, each cell is barcoded to reconstruct the genotype of each cell and the clonality of the tumor. The two-step workflow and proprietary multiplex chemistry unlock access to DNA and more, allowing for high-throughput multi-omics analysis of single cells. Each droplet is discretely optimized for each reaction step: isolation of DNA in the first droplet, followed by targeted PCR of the DNA in the second droplet.


Scientific presentation
CHIP’ing away at somatic mosaicism — Diving into the promises and challenges of characterizing clonal hematopoiesis of indeterminate potential
Ross Levine, MD
Kelly Bolton, MD, PhD
Jyoti Nangalia, MD, PhD
Todd Druley, MD, PhD
Scientific presentation
Meet the Authors: Clonal Heterogeneity in Acute Lymphoblastic Leukemia at Diagnosis and During Chemo Treatment
Jan Cools, PhD, VIB Center for Cancer Biology
Scientific presentation
AMP 2021 Corporate Workshop: Single-cell DNA and multi-omics strategies for untangling therapy-resistant mechanisms in oncology
John Lee, M.D., Ph.D., Fred Hutchinson Cancer Research Center & Julia Gouffon, Ph.D., Mission Bio
Association for Molecular Pathology 2021 Digital Experience (2021)
Scientific presentation
Do More Single Cell with Less – Tapestri Platform Expansion for Hematologic Malignancy Research
Koichi Takahashi, MD, PhD, MD Anderson Cancer Center & Jim Flynn, PhD, Mission Bio