Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
X
X
Scientific presentation

Precision over bulk sequencing


Koichi Takahashi, MD
Dennis Eastbur, PhD
Jerry Radich, MD

Description

Fifty percent (50%) of patients with acute myeloid leukemia (AML) relapse and develop a more virulent form of the disease. To better understand AML and the cancer hematological ecosystem, it is necessary to discern clonal architecture and the dynamics of competing clones, which provide valuable insight into therapy response. It takes three or more mutations for leukemia to form. This can occur in the same cell or within the tumor microenvironment, but how do you discern this information with bulk sequencing? Dr. Jerry Radich, of Stanford Medical Center, and Dr. Koichi Takahashi, of MD Anderson, share their research on how they identified mutations within rare subclones using single-cell analysis for precision over bulk sequencing.



VIEW


Scientific presentation
From Cells to Cures: Panel Discussion on Advancing Clonal Profiling in Leukemia & Myeloma With Single-Cell Multiomics
Hervé Avet-Loiseau, MD, PhD
Felipe Prósper, MD, PhD
Cedric Dos Santos, PhD
Todd Druley, MD, PhD
(2023)
Scientific presentation
Single Cell Multi-Omics & the MRD Horizon
Todd Druley, MD, PhD
Blake Alexander
(2023)
Scientific presentation
Myeloma Matters: Advancing Research and Therapy Development with Single-cell DNA + Protein Multi-Omics
Todd Druley, MD, PhD
Adam Sciambi, PhD
(2023)
Scientific presentation
scTAM-seq: A Novel Method for Profiling DNA Methylation in Single Cells
Michael Scherer, PhD
Agostina Bianchi
(2023)
REQUEST QUOTE