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Announcing the new Tapestri scMRD Assay for AML. Learn More
Scientific presentation

Profiling clonal hematopoiesis in cancer survivors with single-cell DNA sequencing

Chuck Gawad, MD, PhD

St. Jude’s has been treating pediatric cancer for approximately 60 years. Studies have shown that alkylating agents cause mispairings and further mutagenesis, which is associated with cardiac dysfunction and other chronic health conditions. Dr. Gawad’s lab has been working on using single-cell DNA sequencing, which can provide a high-resolution view of the clonal diversity present in our hematopoietic cells as we age, in addition to the occurrence of co-mutations. The hope is to obtain new insight into chronic medical conditions of childhood cancer survivors.


Scientific presentation
AML Single-cell Multi-omics MRD (scMRD) and the Horizon of Clinical Utility
Aaron Llanso
AMP 2022 (2022)
Scientific presentation
Molecular Analysis of Acute Myeloid Leukemia in Morphologic Remission
Sanam Loghavi, MD
AMP 2022 (2022)
Scientific presentation
Considerations, Strategies, and Advances in Early Drug Development to Mitigate Clinical Holds and Achieve Successful CGT Outcomes
Azadeh Golipour, PhD, AVROBIO
J. Kelly Ganjei, AmplifyBio
Scott R. Burger, MD, Advanced Cell and Gene Therapy
Matthew Cato
Scientific presentation
Overview on Mission Bio’s Applications
Simone Formisano
Mission Bio EU Heme Symposium (2022)