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Scientific presentation

Unlocking the power of single-cell DNA analysis with simple software


Anup Parikh, PhD
Description

Recent advances in molecular biology and microfluidics have enabled us to individually sequence the molecular contents of thousands of single cells using single-cell technology. Innovative technologies for single nucleotide variants (SNV) and indel analysis allow researchers to explore single-cell biology by simultaneously identifying the mutation profile within clonal populations, detect f rare subclones, and unambiguous determination of zygosity. These datasets promise to transform our understanding of cellular diversity, but the scale and complexity pose new bottlenecks for data processing and interpretation.



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