technical note

Single-cell DNA sequencing resolves the genetic complexity underlying CLL progression

Co-occurrence and zygosity of mutations in subclonal populations are frequently missed with bulk sequencing. In high-count monoclonal B-cell lymphocytosis (MBL), these mutations were detectable across all patient samples, on average 41 months prior to chronic lymphocytic leukemia (CLL) progression as a result of single-cell analysis. Learn how the Tapestri Single-cell DNA CLL Panel was used to both gain further insights into patient samples and correlated with a deep targeted sequencing approach.

technical note

Assessment of Whole-Genome Copy Number Variation with Tapestri Single-Cell Analysis

technical note

Beyond basic characterization: the synergistic power of Tapestri and patient-derived xenografts to accelerate drug discovery

technical note

High-throughput assessment of genome edited cells with Tapestri antibody hashing

technical note

Unprecedented Resolution of Genome Editing Outcomes with Single-cell Analysis

Single-cell DNA sequencing resolves the genetic complexity underlying CLL progression

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