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technical note

Single-cell DNA analysis of myelodysplastic syndrome using the Tapestri Single-cell DNA AML Panel

Accumulation of genetic mutations can occur during clonal expansion of aberrant cells, leading to a heterogeneous mixture of affected cells that can change a patient’s prognosis. Clonal lineage reconstruction provides a more comprehensive picture of the disease progression. Distinguishing mutational status at the single-cell level offers precision in diagnosis and informs treatment options. Learn how the Tapestri Single-cell DNA AML Panel was used to examine 2 patients with myelodysplastic syndrome (MDS).


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technical note
In-depth quantification of cell and gene therapy DNA integrations enabled with single-cell sequencing
technical note
Deep understanding of cell and gene therapy genome editing protocols enabled with single-cell sequencing
technical note
Model organisms and patient-derived xenografts for preclinical oncology research
technical note
Correlations between genomic variants and protein expression in AML patient samples
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