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technical note

Single-cell DNA analysis of myelodysplastic syndrome using the Tapestri Single-cell DNA AML Panel

Accumulation of genetic mutations can occur during clonal expansion of aberrant cells, leading to a heterogeneous mixture of affected cells that can change a patient’s prognosis. Clonal lineage reconstruction provides a more comprehensive picture of the disease progression. Distinguishing mutational status at the single-cell level offers precision in diagnosis and informs treatment options. Learn how the Tapestri Single-cell DNA AML Panel was used to examine 2 patients with myelodysplastic syndrome (MDS).


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technical note
Model organisms and patient-derived xenografts for preclinical oncology research
technical note
Correlations between genomic variants and protein expression in AML patient samples
technical note
AML subpopulations defined by SNV, CNV, and protein expression
technical note
Copy number variants (CNV) and single nucleotide variants (SNV) simultaneously detected in single cells
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