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High-throughput single-cell targeted DNA sequencing using an updated Tapestri platform reveals rare clones and clonal evolution for multiple blood cancers

Nianzhen Li

The challenge in precision medicine has been improving the understanding of cancer heterogeneity and clonal evolution, which has major implications in targeted therapy selection and disease monitoring. Single-cell sequencing has the potential to provide unique insights on the cellular and genetic composition, drivers, and signatures of cancer at unparalleled sensitivity.

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High-throughput single-cell targeted DNA sequencing using an updated Tapestri platform reveals rare clones and clonal evolution for multiple blood cancers

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