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poster

High-throughput single-cell targeted DNA sequencing using an updated Tapestri platform reveals rare clones and clonal evolution for multiple blood cancers


Nianzhen Li
AACR (2019)

The challenge in precision medicine has been improving the understanding of cancer heterogeneity and clonal evolution, which has major implications in targeted therapy selection and disease monitoring. Single-cell sequencing has the potential to provide unique insights on the cellular and genetic composition, drivers, and signatures of cancer at unparalleled sensitivity.


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poster
Amplicon design algorithm for single cell targeted DNA sequencing using machine learning
Shu Wang
AACR (2020)
poster
Improvements in variant calling sensitivity and specificity in single-cell DNA sequencing using deep learning
Manimozhi Manivannan
AACR (2020)
poster
Powerful insights with single-cell multi-omics: Co-detecting both genotype and phenotype from the same cell
James Flynn, PhD
AGBT (2020)
poster
Subclonal identification of driver mutations and copy number variations from single-cell DNA sequencing of tumors
James Flynn, PhD
ABRF (2020)
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