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Announcing new Tapestri Platform updates including lowered input threshold and expanded heme-onc menu. Learn More
RESEARCHER spotlight
Asiri Ediriwickrema, MD
Stanford University

Enhance the clinical evaluation of AML MRD by uncovering clonality

Minimal Residual Disease (MRD) detection and monitoring hold great promise to be used in clinical trials and beyond patient therapy selection. If single nucleotide variants (SNVs) are detected early on, then better patient stratification and treatment options may be employed to try and prevent relapse. Dr. Asiri Ediriwickrema, from Ravindra Majeti lab at Stanford University, showcases his recent publication in the journal Blood Advances, where they consider how single-cell DNA sequencing enhances MRD detection.

RESEARCHER spotlight
Two mutations in RNA splicing factors from the same cell confirmed with single-cell DNA-Seq
Justin Taylor, MD
University of Miami
RESEARCHER spotlight
Using CRISPR to understand different combinations of gene alterations
John Lee, MD, PhD
Fred Hutch
RESEARCHER spotlight
Single-cell analysis reveals extensive proteogenomic decoupling in leukemia
Adam Abate, PhD; Ben Demaree; Cyrille Delley
RESEARCHER spotlight
How do you decipher and target clonal evolution in myeloid malignancies?
Ross Levine, MD
Memorial Sloan Kettering Cancer Center