Tapestri single-cell DNA panels and protein panels are highly sensitive and customizable panels that enable true multi-omics analysis on the Tapestri Platform. Whether identifying co-mutation patterns and zygosity in subclones or cellular identities and subtle cell states, Tapestri single-cell DNA panels and protein panels can be applied across a wide range of discovery and translational research applications.
Identify SNVs, indels, CNVs, LOH, and translocations from the DNA of thousands of individual cells
Incorporate protein panels and a simple cell-staining protocol to profile genotype and phenotype simultaneously in single cells
Focus on your regions of interest with targeted content that allows flexibility in experimental design and budget
Tapestri Single-cell DNA panels are available in a ready-to-ship or build-to-order format. Select from Tapestri Single-cell DNA Catalog Panels predesigned and wet lab-tested to get your lab up and running with minimal time and effort. With the new Tapestri Single-cell DNA Published Panels, researchers of hematologic malignancies can now easily start with single-cell DNA panels designed by leading researchers and verified for performance through a peer-review publication. If you require more flexibility, consider the predesigned but customizable Tapestri Single-cell DNA Virtual Design Panels. For maximum versatility, create a Tapestri Single-cell DNA Custom Panel for human, mouse, or any other reference genome of your choice.
Oligo-conjugated antibodies from BioLegend can be integrated into your Tapestri experiments to enable concurrent measurement of proteins, uncovering both genotypes and phenotypes from the same cell, across thousands of cells.
Explore our featured panels designed for advanced hematological and genome integrity research. From comprehensive cancer panels to genome stability assays, our solutions offer unparalleled insights for groundbreaking discoveries and clinical advancements.
Clonal evolution is foundational to disease progression in hematologic malignancies, which can impact therapy response, resistance, relapse, and residual disease. Tapestri single-cell hematology panels provide insight into disease drivers and mutation patterns missed during bulk sequencing. By interrogating clonal architecture, rare subclones associated with remission and therapeutic resistance can be identified.
Cellular heterogeneity in solid tumor cancers impacts clonal evolution and patient outcomes. Single-cell DNA solid tumor profiling enables high resolution of the genomic diversity in a variety of tumor types by interrogating specific regions in oncogenes and tumor suppressors.
Predesigned and build-to-order panels for additional indications in solid tumors.
Fully customizable panels for maximum flexibility. Easily order a custom panel using Tapestri Designer.
Analyzing genome-wide copy number variation (gwCNV) is vital for studying cancer clonal heterogeneity, as it uncovers genetic variations within tumors. Identify subclones and aid in targeted treatment strategies. Additionally, gwCNV analysis can help ensure the safety of gene-edited and stem-cell therapies by monitoring genomic stability and avoiding potential oncogenic risks.
With the intuitive Tapestri Designer software, your custom design can be completed easily. Primer design algorithms and multiplex PCR biochemistry have been optimized for the Tapestri Platform so that you can be confident of high design coverage and high panel uniformity. Design a DNA panel against human, mouse, or any other custom reference genomes of your choice. Custom DNA panels can be paired with oligo-conjugated antibodies to enable simultaneous detection of genotype and phenotype from the same cell for true single-cell multi-omics insights.
Providing cancer researchers with the only single-cell multi-omics solution that simultaneously detects SNV, CNV, and protein data from the same cell.